Results 81 to 90 of about 196,587 (341)
Advanced Science, EarlyView.PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Inter-Texting Cultures during Pandemic(s): A Pragmatic Approach and Beyond [PDF]
Cultural Intertexts, 2020 Pandemics are characteristic of both The Roaring 20s, with 1920 being the aftermath of the Spanish flu, and 2020s being the onset of the SARS-CoV-2 pandemic.
Daniela ŞORCARU
doaj
The Role of the Unconscious in the Perception of Risks [PDF]
, 1995 Dr. Fritzsche argues that our world is too rational and that the psychology of the unconscious, as developed by Jung, can be key to understanding responses to hazards and to resolving conflicts that arise in the political management of ...
Fritzsche, Andrew F.
core +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Archetypal Metaphors in Religious Dialogue: A Jungian and Conceptual Blending Analysis [PDF]
نشریه پژوهشهای زبانشناسیBeing rooted in imagery and metaphor, Jungian psychology suggests that metaphors are expressions of archetypal imagery. While extensive research has examined how archetypal theory informs literal metaphors across various languages, less attention has ...
Zahra Asadian Esfahani
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Culture Differences and Tax Morale in the United States and Europe [PDF]
, 2004 In recent years much research has investigated whether values, social norms, and attitudes differ across countries and whether these differences have measurable effects on economic behavior. One area in which such studies are particularly relevant is tax
Benno Torgler, James R. Alm
core
Advanced Science, EarlyView.This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang +15 more
wiley +1 more source
The Multidirectionality of Memory: Networks of Trauma in Post-9/11 Literature
Miscelánea: A Journal of English and American Studies, 2014 9/11 fictional literature shows a striking propensity to conjure up other, historically older traumata and intertextual references in an associative framework which moreover introduces into the texts an oscillation between narrative representation and ...
Katharina Donn
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