Results 91 to 100 of about 163,799 (293)

The Effect of Teaching Metacognitive Listening Strategy during Shadowing Activity on Field-Dependent and Field-Independent EFL Learners’ Listening Comprehension [PDF]

Journal of English Language Pedagogy and Practice, 2017
This study aimed to compare the effect of teaching metacognitive listening strategies through shadowing activity on the listening comprehension of field-dependent (FD) and field-independent (FI) EFL learners.
Parastoo Alizadeh Oghyanous, Mona Khabiri   +1 more
doaj  

Hyperbolicity, transitivity and the two-sided limit shadowing property [PDF]

, 2013
We explore the notion of two-sided limit shadowing property introduced by Pilyugin \cite{P1}. Indeed, we characterize the $C^1$-interior of the set of diffeomorphisms with such a property on closed manifolds as the set of transitive Anosov ...
Carvalho, Bernardo
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Motivation and attitude towards shadowing: learners perspectives in Japanese as a foreign language

Asian-Pacific Journal of Second and Foreign Language Education, 2017
Shadowing has increasingly been recognized as an effective practice for developing listening skills in second language learning. However, there is very little study focusing on learners’ psychological aspects in implementing shadowing practice.
Hideki Sumiyoshi, Chavalin Svetanant
doaj   +1 more source

Gluon Shadowing in DIS off Nuclei

, 2008
Within a light-cone quantum-chromodynamics dipole formalism based on the Green function technique, we study nuclear shadowing in deep-inelastic scattering at small Bjorken xB < 0.01.
Arleo F, Arleo F Gousset T, B Z Kopeliovich, De Vries H, Dokshitzer Yu L, Dokshitzer Yu L, Eskola K J, Eskola K J Paukkunen H Salgado C A, Feynman R P, Frankfurt L, Gribov V N, Gribov V N, Gribov V N, I K Potashnikova, Ivan Schmidt, J Nemchik, Kancheli O V, Karmanov V, Kazarinov Yu M, Milner R G, Nemchik J Petracek V Potashnikova I K Sumbera M, Nemchik J Potashnikova I K, Nikolaev N N, Pirner H J Galow B Schlaudt O, Raufeisen J, Yang Hongyan, Zakharov B G, Zamolodchikov A B   +27 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Bimodal Porosity and Stability of a TiO₂ Gig-Lox Sponge Infiltrated with Methyl-Ammonium Lead Iodide Perovskite

Nanomaterials, 2019
We created a blend between a TiO2 sponge with bimodal porosity and a Methyl-Ammonium Lead Iodide (MAPbI3) perovskite. The interpenetration of the two materials is effective thanks to the peculiar sponge structure. During the early stages of the growth of
Salvatore Sanzaro, Federico Zontone, David Grosso, Thomas Bottein, Fortunato Neri, Emanuele Smecca, Giovanni Mannino, Corrado Bongiorno, Corrado Spinella, Antonino La Magna, Alessandra Alberti   +10 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source