Results 31 to 40 of about 78,110 (303)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Journal of Mechanical Engineering, 2023 One of the important directions of theoretical, computational and experimental research related to the improvement and development of new design elements of modern electrical devices, primarily medium voltage circuit breakers and contactors, is the study
Yevhen I. Baida +2 more
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Very high voltage latching relay [PDF]
, 1974 Relay consists of high voltage reed switch actuated by rotating permanent magnet mounted on stepper motor shaft, with actuation assembly isolated from high voltage circuit.
Lovell, R. R. +2 more
core +1 more source
Energies, 2020 Common-mode voltage, caused by a 2-level inverter, is a source of discharge currents in motor bearings. Due to the capacitive coupling, between the stator winding and the rotor, an image of the common-mode voltage is produced on the shaft—which can ...
Jan Ole Stockbrügger, Bernd Ponick
doaj +1 more source
Radial displacement sensor for non-contact bearings [PDF]
, 1998 A radial position sensor includes four capacitive electrodes oriented about a shaft, arranged in two diametrically opposite pairs. Sensor circuitry generates an output signal in proportion to the capacitance between the electrodes and the shaft; the ...
McCormick, John A., Sixsmith, Herbert
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Controller for computer control of brushless dc motors [PDF]
, 1981 A motor speed and torque controller for brushless d.c. motors provides an unusually smooth torque control arrangement. The controller provides a means for controlling a current waveform in each winding of a brushless dc motor by synchronization of an ...
Hieda, L. S.
core +1 more source
Solar Splash Senior Design Project [PDF]
, 2020 Indiana University Purdue University IndianapolisThe Solar Splash senior project is the first attempt at creating an entirely solar propelled watercraft.
Almogayer, Khaled +2 more
core
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source