Results 141 to 150 of about 17,254 (263)

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Rough and Tough: How Particle Surface Roughness Affects Liquid Marble Formation and Stability

Advanced Science, EarlyView.
This study investigates the influence of particle surface roughness on the formation and stability of liquid marbles using well‐defined colloidal supraparticles as model systems. Increasing surface roughness enhances the interfacial contact angle, improves mechanical stability by increasing deformation resistance upon impact, and enables liquid marble ...
Umair Sultan, Celin Kotulla, Kall Kefle, Syuji Fujii, Nicolas Vogel   +4 more
wiley   +1 more source

A Universal and Versatile Zwitterionic Coating for Blood‐Contacting Catheters with Long Lengths and Complex Geometries

Advanced Science, EarlyView.
A universal and versatile zwitterion coating strategy is developed for blood‐contacting catheters with long lengths and complex geometries. The coating exhibits near‐zero fouling, superior anticoagulation, and selective biocapturing properties while maintaining excellent stability under dynamic blood flow.
Tong Zhang, Tian Liang, Qichao Pan, Shouyan Zhang, Shuhua Zhang, Zhi Geng, Bo Zhu   +6 more
wiley   +1 more source

Multi-lab intrinsic solubility measurement reproducibility in CheqSol and shake-flask methods. [PDF]

ADMET DMPK, 2019
Avdeef A.
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Shake flask methodology for assessing the influence of the maximum oxygen transfer capacity on 2,3-butanediol production. [PDF]

Microb Cell Fact, 2019
Heyman B, Lamm R, Tulke H, Regestein L, Büchs J.   +4 more
europepmc   +1 more source

Dynamic Molecular Cocrystals with Alkyl Chain Dependent Thermosalient Phase Transitions

Advanced Science, EarlyView.
A series of cocrystals containing 5‐fluorocytosine and fatty acids with varying alkyl chain lengths are synthesized, demonstrating a systematic modulation of thermosalient phase transition temperatures across a broad range (≈100 K). This study reveals a linear correlation between interlayer hydrophobic interactions and transition temperatures, offering
Jiantao Meng, Yuan Su, Hang Zhu, Jie Zhang, Ting Cai   +4 more
wiley   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

Conjugated Carbonyl Compound‐Enhanced Hydrogels for Tactile Recognition

Advanced Electronic Materials, EarlyView.
The (PAA‐2DC)‐Fe3+/PEDOT: PSS hydrogel is constructed by incorporated PI‐COF into the PAA‐based double network hydrogel, the presence of metal coordination bonds, hydrogen bonds, and a π–π conjugate system imparts excellent flexible sensing properties to the hydrogel, while demonstrating its ability to differentiate between materials of different sizes
Xue‐Qing Zhan, Han Chen, Zhi‐Ling Hong, Yong‐Ping Leng, Chang‐Chang Zhu, Chang‐Bo Zhang, Zhong‐Xiang Tang, Qian Chen, Ning Ma, Fang‐Chang Tsai   +9 more
wiley   +1 more source

Immobilization and Application of Fatty Acid Photodecarboxylase in Deep Eutectic Solvents

ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
The recently discovered fatty acid photodecarboxylase shows great promise for the synthesis of drop‐in fuels, but several factors limit its applicability, such as poor photostability and poor solubility of the substrates. In this work we show, for the first time, its immobilization in a solid carrier, and its applicability in deep eutectic solvents ...
Santiago Nahuel Chanquia, Frederik Vig Benfeldt, Noémi Petrovai, Paul Santner, Frank Hollmann, Bekir Engin Eser, Selin Kara   +6 more
wiley   +1 more source