Biotechnology and Bioengineering, EarlyView.ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev +6 more
wiley +1 more source
Recombinant production of acidophilic L-arabinose isomerase from Lentilactobacillus parakefiri in Bacillus subtilis. [PDF]
Microb Cell FactWeber N +4 more
europepmc +1 more source
BMEMat, EarlyView.An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu +5 more
wiley +1 more source
Synthesis of tunable copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate by engineered <i>Halomonas bluephagenesis</i> and their characterizations. [PDF]
Synth Syst BiotechnolLi S +11 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Synergistic strategies for high production of Geobacillus stearothermophilus α-amylase in Bacillus subtilis. [PDF]
J Ind Microbiol BiotechnolRao D +8 more
europepmc +1 more source
Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes
Biotechnology Progress, EarlyView.Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova +5 more
wiley +1 more source
Combining computer-aided enzyme design and chromosomal integration for plasmid-free biosynthesis of 1,5-pentanediol in Escherichia coli. [PDF]
Microb Cell FactDeng H +10 more
europepmc +1 more source
Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach
Biotechnology Progress, EarlyView.Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya +7 more
wiley +1 more source
Acetate-containing supernatants from industrial off-gas cultivation enabling high-value product formation with established and emerging production organisms. [PDF]
Biotechnol Biofuels BioprodStrehl L +6 more
europepmc +1 more source