Results 31 to 40 of about 234,485 (218)

Benefication of low-grade chromite ores of abandoned mine at Topraktepe, Beyşehir, SW Turkey [PDF]

Acta Montanistica Slovaca, 2007
Optimum enriching possibilities of chromite ores from the abandoned Topraktepe mine were investigated. To obtain the best enriching method(s), shaking table, multi gravity separator, humprey spiral and jigging tests were tested. The best grades for Cr2O3
Tevfik Agacayak, Veysel Zedef, Salih Aydogan   +2 more
doaj  

Influence of the Duration Compression Ratio of the Input Motion on the Seismic Response of a Soil–Pile–Bridge Structure System in Shaking Table Tests

Applied Sciences, 2022
In the shaking table test of a soil–pile–bridge structure system, it is difficult to keep the similarity relations of the model structure and that of the model soil consistent.
Zhi Zhang, Chenning Song, Xiaojun Li, Xingjun Qi   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Resonance Suppression for Hydraulic Servo Shaking Table Based on Adaptive Notch Filter

Shock and Vibration, 2019
In dynamic structure test, the specimen of hydraulic servo shaking table contains not only inertia load but also elastic load. The specimen herein is simplified as a spring-mass-damping system, and the mathematical model of the hydraulic servo shaking ...
Jianjun Yao, Zhenshuai Wan, Yue Zhao, Jie Yu, Chen Qian, Yu Fu   +5 more
doaj   +1 more source

Numerical simulation of irregular section underground structure shaking table test model

Earthquake Research Advances, 2022
Based on the the large shaking table test results on irregular section subway station structure in soft soil, an overall time-history numerical simulation is conducted to study the nonlinear dynamic interaction of the soil-irregular underground structure.
Baizan Tang, Wenchao Deng, Su Chen, Xiaojun Li, Haiyang Zhuang   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A New Control Technology of Shaking Table Based On the Jerk

工程科学与技术, 2018
Shaking table test is a direct and effective means of seismic response simulation and seismic performance observation of engineering structures,but because the electro-hydraulic servo shaking table system is complex nonlinear system,the performance of ...
Xiaojun LI, Fangfang LI, Jinbao JI, Juke WANG   +3 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Application and Analyzation of the Vision-Based Structure Model Displacement Measuring Method in Cassette Structure Shaking Table Experiment

Advances in Civil Engineering, 2020
In the shaking table test of large cassette structure, story drift is an essential set of experimental data. The traditional method of displacement measurement is limited to problems such as necessary full contact with the structure model for ...
Wang Yanhua, Wang Cheng, Feng Yan, Dai Bowen, Wu Gang   +4 more
doaj   +1 more source