Results 61 to 70 of about 8,220,657 (249)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Numerical Simulation of Shaking Table Test by Nonlinear Response Analysis Method [PDF]
, 1991 In this paper we described the results or numerical simulation or shaking table test on two dimensional soil-structure interation system to verify an application or newly developed nonlinear response analysis method.
Ohnami, Masayuki +4 more
core +1 more source
Development and performance tests on NS-2 horizontal unidirectional centrifugal shaker
Yantu gongcheng xuebao, 2020 The dynamic centrifuge model test technology based on the geo-centrifugal shaking table system is the most effective and advanced research method and test technology for geotechnical engineering seismic problems.
GU Xing-wen , REN Guo-feng , WANG Nian-xiang , XU Guang-ming
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Experiment program of shake table test on a precast frame made of recycled aggregate concrete
Ho Chi Minh City Open University Journal of Science - Engineering and Technology, 2016 A precast frame model made of Recycled Aggregate Concrete (RAC) been constructed with precast beams, columns and Cast-In-Place (CIP) joints. Then a shaking table test was carried out with three types of earthquake ground motions, namely Wenchuan, El ...
Pham Thi Loan, Phan Van Hue
doaj
PFC Simulation on Shaking Table Concrete-Faced Rockfill Dam Model Test
, 2010 The shape and seismic behavior of concrete-faced rockfill dams under designed seismic load are usually studied by shaking table test, dynamic centrifuge model test and finite element dynamic analysis. Particle flow code (PFC) simulation is analyzed based
Gui Yang, Yu Min Chen, De Qing Gao
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source