Results 51 to 60 of about 12,009 (290)

Pakistan and Regional Cooperation Organizations: Towards a Futuristic Approach

open access: yesPolicy Perspectives, 2017
Pakistan is member of Economic Cooperation Organization (ECO) and South Asian Association for Regional Cooperation (SAARC) for past more than three decades.
Irfan Shahzad
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

open access: yesAdvanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang   +10 more
wiley   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

A comprehensive metric study of distributed PV consumption capacity considering multiple uncertainties

open access: yesEnergy Informatics
With the transformation of the energy structure, distributed photovoltaic (PV) power generation has become increasingly important. However, due to uncertain factors such as weather, equipment, and load demand, the consumption problem is prominent, which ...
Chengmin Wang, Yangzi Wang, Fulong Song
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

US Cooperation with the Shanghai Cooperation Organization: Challenges and Opportunities

open access: yes, 2011
Few regions in the world offer a clearer picture of geopolitical competition than Central Asia. The region plays host to such global powers as the United States, Russia, China, and Indiaâ⿬⿝all states with enormous resources they are willing to expend in ...
Reeves, J.
core  

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

THE INTERESTS OF THE CENTRAL ASIAN STATES AND THE SHANGHAI COOPERATION ORGANIZATION

open access: yesEge Akademik Bakis (Ege Academic Review), 2010
Bu makale Sangai Isbirligi Orgutu ( SIO ) uyesi Orta Asya devletlerinin Orgutun amaclari baglaminda cikarlarinin neler oldugunu arastirmaktadir. Bu calisma orta asya devletlerinin SIO‘ne uyeliklerinin guvenlik ve ekonomik cikarlari,bolgesel isbirligi ve Rusya,Cin ve Amerika Birlesik Devletleri ile dengeli iliskiler icin yararli oldugunu gostermektedir ...
openaire   +6 more sources

The Shanghai Cooperation Organization : is it undermining U.S. interests in Central Asia? : hearing before the Commission on Security and Cooperation in Europe, One Hundred Ninth Congress, second session, September 26, 2006.

open access: yes, 2008
"CSCE 109-2-10."Shipping list no.: 2009-0093-P.Includes bibliographical references.Mode of access ...
United States. Congress. Commission on Security and Cooperation in Europe.
core  

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