Results 51 to 60 of about 10,907 (256)

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Analysis of the Interests of Iran\'s Membership in the Shanghai Cooperation Organization: Computable General Equilibrium (CGE) Approach [PDF]

پژوهشهای اقتصادی, 2022
Iran's membership in Shanghai Cooperation Organization (SCO), in addition to political and security gains, can bring broad economic benefits. In this regard, in this research, the economic impacts of decreasing import tariffs of Iran and the Shanghai ...
Mehdi Nejati, yaser balaghi enalou
doaj  

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

The Shanghai Cooperation Organization: An Emerging Venue for China’s New Diplomacy

China Quarterly of International Strategic Studies, 2020
China’s increasing strategic investment and continued diplomatic outreach has indicated that it aims to play a larger leadership role in global affairs in the years to come.
Enayatollah Yazdani
doaj   +1 more source

UZBEKISTAN - SHANGHAI COOPERATION ORGANIZATION: MUTUAL COOPERATION FOR PEACE

, 2022
The Shanghai Cooperation Organization is a unique political structure that has become an integral part of the world from a global, political and economic point of view for more than 20 years. Of course, the location of this organization indicates a lot.
Dilmurodov Dilmurod Dilshodjon Ugli, Imamov Javoxir Fayozovich   +1 more
openaire   +2 more sources

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Shanghai Cooperation Organization and Turkey Relations

Resolusi: Jurnal Sosial Politik, 2019
At the beginning of the 1990s, collapsing of the USSR caused huge disappointment also political disorder and problems. To solve treacherous conditions and border disputes, joint actions were implemented by China and Russia. As a result, the Shanghai Cooperation Organization was established.
openaire   +2 more sources

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

10 Years of University of Shanghai Cooperation Organization: Main Results

RUDN Journal of World History, 2017
The article reviews the main results of the activities of the University of the Shanghai Cooperation Organization (SCO) over a ten-year period, analyzes the effectiveness of its activities and the results of the universities participating in the SCO ...
L I Efremova, R G Fedorov
doaj   +1 more source