Results 71 to 80 of about 12,009 (290)

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Pola Perimbangan dan Regionalisasi Sektor Pertahanan di Shanghai Cooperation Organization

, 2018
Abstrak – Tulisan ini berusaha memahami dua hal, yakni pola perimbangan dan regionalisasi sektor pertahanan di Shanghai Cooperation Organization (SCO), sebuah organisasi regional yang beranggotakan China, Russia, Kazakhstan, Kirgistan, Uzbekistan ...
Halkis, Mhd, Gumilar, Nugraha, Akhli, Rangga Amalul   +2 more
core   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Shanghai Cooperation Organization: Origin, Transformation, and Discussions on Expansion(s)

Bölge Çalışmaları Dergisi
This article mainly examines the establishment, transformation, and expansion of the Shanghai Cooperation Organization. In this respect, the article focuses on the four cumulative steps. The first of these investigates the security concerns of the states
Merve ERKAN AYDIN, Yi LIU
doaj  

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Palladium‐Doping‐Enabled Interface Synergy for Superb Ampere Level Ammonia Electrosynthesis From Nitrate

Angewandte Chemie, EarlyView.
Isolated Pd sites in a metallic Co matrix boost nitrate‐to‐ammonia conversion. Pd doping optimizes intermediate adsorption and reconstructs the interfacial microenvironment, promoting cation enrichment and a hydrogen‐down‐oriented water network. This dual modulation facilitates proton transfer and intermediate stabilization, enabling high ammonia ...
Qun He, Chuanqiang Wu, Zhangsheng Shi, Dongxue Yu, Wei Jiang, Li Song, Xin Wang   +6 more
wiley   +2 more sources

The Shanghai Cooperation Organization amidst the Rising International Tensions

Journal of Eurasian Studies
The Shanghai Cooperation Organization (SCO), established over two decades ago, stands as one of the most prominent international entities within the non-Western geopolitical sphere.
Alexander Lukin, Dmitry Novikov, Olga Puzanova, Shamil Yenikeyeff   +3 more
doaj   +1 more source

Legal Framework and Developing Part of Trade Facilitation in the Shanghai Cooperation Organization

Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì
 The Shanghai Cooperation Organization’s Inaugural Declaration explicitly initiated negotiations on investment facilitation, a theme consistently reaffirmed in subsequent heads of state declarations.
Сюэ Ли, Цзянь Ву
doaj   +1 more source

Монгол Улсын Ерөнхийлөгч Ц.Элбэгдоржийн Шанхайн хамтын ажиллагааны байгууллагын гишүүн орнуудын төрийн тэргүүн нарын зөвлөлийн 12 дугаар хуралдаан дээр хэлсэн үг

Олон улс судлал, 2021
English title: Remarks by Elbegdorj Tsakhia, President of Mongolia, at the 12th meeting of Council of Heads of Member States of Shanghai Cooperation ...
Elbegdorj Ts
doaj  

NETWORK UNIVERSITY OF THE SHANGHAI COOPERATION ORGANIZATION

ICERI Proceedings, 2017
The article deals with the urgent problem of the development of the countries' inter-university cooperation of the Shanghai Cooperation Organization (SCO) at the present stage in the context of their humanitarian cooperation. The realities of the globalizing world suppose the development of interaction between people who are at great distances from ...
Egorova M., Barov S., Pospelova J., Shabanova A.   +3 more
openaire   +2 more sources