Results 121 to 130 of about 88,634 (286)
AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
Advanced Intelligent Discovery, EarlyView.To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source
Ìнформаційні технології та компʼютерна інженеріяThe transformation of contemporary corporate IT infrastructures has rendered conventional cybersecurity models ineffective, prompting a shift to the Zero Trust Architecture (ZTA); however, its practical implementation is complicated by a rigid reliance ...
A. Palamarchuk
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.An explainable CatBoost model was trained to predict the bandgaps of 474 phosphate crystals based on composition and density descriptors. SHAP analysis identified two key variables—d‐electron‐count dispersion and atomic‐density dispersion—as the primary drivers of the model's predictions.
Wenhu Wang +3 more
wiley +1 more source
Two-Level Ensemble with Four Meta-Features for Diabetes Classification on Clinical Tabular Data
Journal of Applied Informatics and ComputingDiabetes mellitus remains a major global public health challenge due to its increasing prevalence, high risk of chronic complications, and growing burden on healthcare systems.
Farid Ma'ruf +2 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi +2 more
wiley +1 more source
A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.A novel hybrid transfer learning approach for brain tumor classification achieves 99.47% accuracy using magnetic resonance imaging (MRI) images. By combining image preprocessing, ensemble deep learning, and explainable artificial intelligence (XAI) techniques like gradient‐weighted class activation mapping and SHapley Additive exPlanations (SHAP), the ...
Sadia Islam Tonni +11 more
wiley +1 more source
Frontiers in OncologyPurposeRadical cystectomy (RC) is the standard treatment for muscle-invasive and select high-risk non–muscle-invasive bladder cancer. Despite definitive surgery, recurrence and progression remain major clinical concerns.
Jian Hou +9 more
doaj +1 more source
Advanced Intelligent Systems, EarlyView.A machine learning‐driven digital twin simulates an aptamer‐functionalized BioFET measuring 17β‐estradiol. Real‐time Isd signals are processed, features are extracted, and trained models estimate hormone concentration. In parallel, a one‐step‐ahead forward model learns biosensor dynamics and generates realistic synthetic signals, enabling in silico ...
Anastasiia Gorelova +4 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.Droplet‐based microfluidics enables precise, high‐throughput microscale reactions but continues to face challenges in scalability, reproducibility, and data complexity. This review examines how artificial intelligence enhances droplet generation, detection, sorting, and adaptive control and discusses emerging opportunities for clinical and industrial ...
Junyan Lai +10 more
wiley +1 more source