Results 61 to 70 of about 221,329 (275)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Negative property of shape-preserving finite-dimensional linear operators

Applied Mathematics Letters, 2003
The paper deals with a linear operator \(L_n:C^k[0,1]\mapsto C^k[0,1]\), of finite rank \(n+1\), which satisfies \(D^kL_ne_k=D^ke_k\), where \(e_i(x):=x^i\), \(i\geq0\), and \(D^k\) denotes the \(k\)th derivative. If the operator preserves a certain cone \(C_{h,k}(\sigma)\) (described below), then the main result claims that not all the \(k\)th ...
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Note on the shape-preservation of a new class of Kantorovich-type operators via divided differences

Demonstratio Mathematica
Shape-preserving approximation is a significant approximation method that has many application areas, such as computer-based geometric design, image processing, geodesy, chemistry, and robotics.
Turhan Nezihe
doaj   +1 more source

Dynamic distance-based shape features for gait recognition [PDF]

, 2014
We propose a novel skeleton-based approachto gait recognition. The core of our method consists ofemploying the screened Poisson equation for construct-ing a family of smooth distance functions associatedwith a given shape.
Robertson, Neil M., Alexander Belyaev, Robertson, Neil, Whytock, Tenika, Tenika Whytock, Neil M. Robertson, Belyaev, Alexander   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

(λ, ψ)-Bernstein-Kantorovich operators

Demonstratio Mathematica
In this article, we introduce a new family of (λ,ψ)\left(\lambda ,\psi )-Bernstein-Kantorovich operators which depends on a parameter λ\lambda , derived from the basis functions of Bézier curves and an integrable function ψ\psi .
Aktuğlu Hüseyin, Kara Mustafa, Baytunç Erdem, Fidan Saner   +3 more
doaj   +1 more source

Epoxy/Polycaprolactone Systems with Triple-Shape Memory Effect: Electrospun Nanoweb with and without Graphene Versus Co-Continuous Morphology [PDF]

, 2013
Triple-shape memory epoxy (EP)/polycaprolactone (PCL) systems (PCL content: 23 wt %) with different structures (PCL nanoweb embedded in EP matrix and EP/PCL with co-continuous phase structure) were produced.
Márta Fejős, Molnár, Kolos, Kolos Molnár, József Karger-kocsis, Karger-Kocsis, József, Fejős, Márta   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source