Results 161 to 170 of about 24,822,268 (298)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Discussion of "LESA: Longitudinal Elastic Shape Analysis of Brain Subcortical Structures". [PDF]

J Am Stat Assoc, 2023
Zhang D, Kang J.
europepmc   +2 more sources

Impact of weight-bearing on foot shape: a geometric and morphometric assessment using principal polynomial shape analysis. [PDF]

Sci Rep
Li J, Bonte C, Audenaert E, Burssens A, Peiffer M, Huysentruyt R, Van den Borre I, Van Oevelen A, Duquesne K.   +8 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Hippocampal subfield thickness and shape analysis in examining the impact of TDP-43 in primary age-related tauopathy. [PDF]

Alzheimers Dement
Youssef H, Gatto RG, Petersen RC, Reichard RR, Jack CR, Whitwell JL, Josephs KA.   +6 more
europepmc   +1 more source

Optimal designs for 3D shape analysis with spherical harmonic descriptors [PDF]

We determine optimal designs for some regression models which are frequently used for describing 3D shapes. These models are based on a Fourier expansion of a function defined on the unit sphere in terms of spherical harmonic basis functions.
Dette, Holger, Pepelyshev, Andrey, Melas, Viatcheslav B.   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Geometric moment-based spectral descriptors for robust non-rigid 3D shape analysis. [PDF]

Sci Rep
Zhang D, Liu N, Wu Z, Lv C, Zhao D.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Shape analysis of the amygdala, hippocampus and thalamus in former American football players. [PDF]

Brain Commun
John O, Wickham A, Jung LB, Mirmajlesi AS, Stearns J, Breedlove K, Kim N, Daneshvar DH, Billah T, Pasternak O, Chamaria A, Coleman MJ, Tripodis Y, Adler CH, Bernick C, Balcer LJ, Rushmore RJ, Alosco ML, Koerte IK, Lin AP, Cummings JL, Reiman EM, Stern RA, Shenton ME, Arciniega H, Bouix S, DIAGNOSE CTE Research Project .   +26 more
europepmc   +1 more source