Results 201 to 210 of about 1,349,497 (315)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A Wasserstein-Type Distance for Gaussian Mixtures on Vector Bundles with Applications to Shape Analysis. [PDF]

SIAM J Imaging Sci
Wilson M, Needham T, Park C, Kundu S, Srivastava A.   +4 more
europepmc   +1 more source

Intrinsic Measures and Shape Analysis of the Intratemporal Facial Nerve

, 2020
Thomas J. Hudson, Bradley Gare, Daniel Allen, Hanif M. Ladak, Sumit Agrawal   +4 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Hardware Acceleration of Digital Pulse Shape Analysis Using FPGAs. [PDF]

Sensors (Basel)
González C, Ruiz M, Carpeño A, Piñas A, Cano-Ott D, Plaza J, Martinez T, Villamarin D.   +7 more
europepmc   +1 more source

Performance Analysis of Object Shape Classification and Matching from Tactile Images Using Wavelet Energy Features

, 2013
Shreyasi Datta, Anwesha Khasnobish, Amit Konar, D. N. Tibarewala, R. Janarthanan   +4 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Dynamic protein-protein interactions of KCNQ1 and KCNE1 measured by EPR line shape analysis. [PDF]

Biochim Biophys Acta Biomembr
Stowe RB, Bates A, Cook LE, Dixit G, Sahu ID, Dabney-Smith C, Lorigan GA.   +6 more
europepmc   +1 more source

Fetal face shape analysis from prenatal 3D ultrasound images

, 2023
Sivera R, Clark AE, Dall'Asta A, Ghi T, Schievano S, Lees CC.   +5 more
europepmc   +1 more source

Contour analysis for interpretable leaf shape category discovery [Erratum: Dec. 2019, v.15(1), p.132]

, 2019
Jorge Victorino, Francisco Gómez
openalex   +1 more source