Results 131 to 140 of about 974,120 (307)
Shape manipulation using physically based wire deformations
, 2010 This paper develops an efficient, physically based shape manipulation technique. It defines a 3D model with profile curves, and uses spine curves generated from the profile curves to control the motion and global shape of 3D models.
L. H. You +9 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
This research is an attempt to find an objective system for maintaining cultural identity in design. The proposed framework will guide interior designers to identify the key features and design language of their traditional style, and then to modify it ...
Alsallal, Abdulaziz S.
core
, 2006 This paper deals with two kinds of optimisation problems, relevant to the optimised source distribution and the shape optimum design, using Continuum Design Sensitivity Analysis (CDSA) in combination with standard electromagnetic (EM) software.
Lowther, D.A. +6 more
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A Simulation Method for Design and Development of Magnetic Shape Memory Actuators
The systems/products and their design processes have become more and more complicated due to the fact that their requirements in terms of function, durability, reliability and energy efficiency have been increased significantly and that their leading ...
Schiepp, Thomas
core
Shape Morphing Using PDE Surfaces
, 2006 YesA methodology for shape morphing using partial differential equation (PDE) surfaces is presented in this work. The use of the PDE formulation shows how shape morphing can be based on a boundary-value approach by which intermediate shapes can be ...
Willis, P. +3 more
core
Diff-Shape: A Novel Constrained Diffusion Model for Shape based De Novo Drug Design
Shape-based virtual screening is a widely utilized method in ligand-based de novo drug design, aiming to identify molecules in chemical libraries that share similar 3D shapes but simultaneously possess novel 2D chemical structures compared to the ...
Mingyuan, Xu, Hongming, Chen, Jie, Lin
core +1 more source
Octree-based production of near net shape components
, 2008 Near net shape (NNS) manufacturing refers to the production of products that require a finishing operation of some kind. NNS manufacturing is important because it enables a significant reduction in: machining work, raw material usage, production time ...
Medellin, H. +8 more
core +1 more source
Shape Optimal Design of Involute Gear Fillet
Jixie chuandong, 1996 描述齿根过渡曲线的有理ＥＥ样条的内权因子为设计变量，齿根过渡曲线区域最大ＶｏｎＭｉｓｅｓ应力极小化为目标，应用自适应有限元分析技术，对齿极过渡曲线进行了形状优化设计，获得了具有较高齿根弯曲强度的齿根渡曲线。
郭太勇, 梁迎春, 黎文勇
doaj