Results 41 to 50 of about 3,054 (254)

Algorithmic complexity of shape grammar implementation [PDF]

open access: yes, 2018
Computer-based shape grammar implementations aim to support creative design exploration by automating rule-application. This paper reviews existing shape grammar implementations in terms of their algorithmic complexity, extends the definition of shape ...
Rudi Stouffs, Thomas Wortmann
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Shape Machine and Parametrics [PDF]

open access: yes, 2019
Presented as part of the Shape Machine Symposium on April 11, 2019 at 11:15 a.m. in the John & Joyce Caddell Building, Flex Space.James Park is a PhD Student in the School of Architecture at the Georgia Institute of Technology. His research investigates
Park, James
core  

A shape grammar for self-built housing [PDF]

open access: yes, 2023
This paper describes the initial results of a grammar study based on bottom-up research carried out in Campinas. The research covers self-built housing and “in situ” projects aimed at creating systems which will help the inhabitants by providing them ...
Paio, A., Tching, J., Reis, J.
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Applying shape grammar and BIM for generating the mass modular housing design in ShanLiChenJia village, ZhaoYuan, China

open access: yesJournal of Asian Architecture and Building Engineering
This paper proposes a method for floor plan designs that combines shape grammar with Building Information Modeling (BIM) technology to create plan module libraries by using the mass modular housing project in ShanLiChenJia village as an example.
Jiang Wang, Jiandong Zhou, Sheng Zhang
doaj   +1 more source

An improved generative design approach based on graph grammar for pattern drawing

open access: yesMachine Graphics & Vision
Generative design is used to efficiently generate design solutions with powerful computational methods. Generative design based on shape grammar is currently the most commonly used approach, but it is difficult for shape grammar to formally analyze the ...
Yufeng Liu   +4 more
doaj   +1 more source

Application of shape grammar theory to underground rail station design and passenger evacuation [PDF]

open access: yes, 2012
This paper outlines the development of a\ud computer design environment that generates station ‘reference’\ud plans for analysis by designers at the project feasibility stage.\ud The developed program uses the theoretical concept of shape\ud grammar ...
Smith, Graham   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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