Results 41 to 50 of about 3,334,027 (332)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
gMotion: A spatio-temporal grammar for the procedural generation of motion graphics [PDF]
, 2018 Creating by hand compelling 2D animations that choreograph several groups of shapes requires a large number of manual edits. We present a method to procedurally generate motion graphics with timeslice grammars.
Carra, Edoardo +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Shape grammar for Mies van der Rohe's high-rise apartment [PDF]
, 2007 Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2007.Includes bibliographical references (leaves 49-50).This thesis explores an application of a rule-based method to a practical architecture design.
Moon, Junsik, S.M. Massachusetts Institute of Technology
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Role of Genetic tapes in Building’s Classification (Analytical study of the Arab-Islamic palaces) [PDF]
Engineering and Technology Journal, 2016 The previous knowledge consider architectural form as a text like language texts, which sending messages holds meanings through codes that reflects a set of shapes and relations to the receiver.
Asmaa M.H. Al-Muqaram +1 more
doaj +1 more source
Two types of Cahuilla kinship expressions: inherent and establishing [PDF]
, 1980 In my Cahuilla Grammar (Seiler 1977:276-282) and in a subsequent paper (Seiler 1980:229-236) I have drawn attention to the fact that many kin terms in this language, especially those that have a corresponding reciprocal term in the ascending direction ...
Seiler, Hansjakob
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Buildings, 2023 In Slovenia, the existing organised housing infrastructure for people over 65 years of age is insufficient and lacks diversification. Older people are often homeowners, many of whom dwell in large, underused single-family houses that require adaptations.
Ana Belčič, Sara Eloy
doaj +1 more source