Results 61 to 70 of about 3,054 (254)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Design with shape grammars and reinforcement learning

Advanced Engineering Informatics, 2013
Shape grammars are a powerful and appealing formalism for automatic shape generation in computer-based design systems. This paper presents a proposal complementing the generative power of shape grammars with reinforcement learning techniques. We use simple (naive) shape grammars capable of generating a large variety of different designs.
Manuela Ruiz-Montiel, Javier Boned, Juan Gavilanes, Eduardo Jiménez, Lawrence Mandow, José-Luis Pérez-de-la-Cruz   +5 more
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

JACY - a grammar for annotating syntax, semantics and pragmatics of written and spoken japanese for NLP application purposes [PDF]

, 2006
In this text, we describe the development of a broad coverage grammar for Japanese that has been built for and used in different application contexts.
Siegel, Melanie
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Alberti Digital on Portuguese Architecture: Shape Grammar transformations as computational framework to determine the influence of Alberti’s legacy on Portuguese Renaissance churches

Joelho, 2014
The research described in this paper is part of a project aimed to determine the influence of Alberti’s treatise on Architecture De re aedificatoria (1485) on Portuguese Renaissance architecture, making use of a computational framework. The paper focus
Bruno Figueiredo
doaj   +1 more source

Shape grammar parsing via Reinforcement Learning [PDF]

, 2011
International audienceWe address shape grammar parsing for facade segmentation using Reinforcement Learning (RL). Shape parsing entails simultaneously optimizing the geometry and the topology (e.g.
Panagiotis Koutsourakis, Nikos Paragios, Simon, Loïc, Paragios, Nikos, Olivier Teboul, Koutsourakis, Panagiotis, Teboul, Olivier, Iasonas Kokkinos, Kokkinos, Iasonas, Loic Simon   +9 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

A shape grammar approach to climatically adaptable facade systems with real time performance evaluation. [PDF]

, 2019
New computational techniques have been introduced to assist the design of adaptable building facades and to help quantify relationships between the building envelope and the environment.
TUNG NGUYEN, BORIS CERANIC, CHRISTOPHER CALLAGHAN
core