Results 91 to 100 of about 796,752 (353)

Investigation of ultraviolet radiation effects on thermomechanical properties and shape memory behaviour of styrene-based shape memory polymers and its composite

, 2018
In recent years, shape memory polymers (SMP) have been researched extensively for space applications, such as deployable solar panels and antenna reflectors.
Al Azzawi, Wessam, Epaarachchi, J. A., Leng, Jinsong   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Larger recovery strains in a CoNiSi alloy due to enhanced reversibility of FCC⇌HCP martensitic transformation

Journal of Materials Research and Technology
It is not clear how coherent ordered nanoparticles affect characteristics of FCC⇌HCP martensitic transformation in disordered alloys. In this paper, the precipitations of coherent ordered nanoparticles and their effects on the FCC⇌HCP martensitic ...
Q. Liao, D. Wang, X. Yang, W. He, H.B. Peng, Y.H. Wen   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Effect of WEDM Process Parameters on Surface Morphology of Nitinol Shape Memory Alloy

Materials, 2020
Nickel–titanium shape memory alloys (SMAs) have started becoming popular owing to their unique ability to memorize or regain their original shape from the plastically deformed condition by means of heating or magnetic or mechanical loading.
R. Chaudhari, Jay J. Vora, Vivek K. Patel, L. L.N., pez de Lacalle, D. M. Parikh   +5 more
semanticscholar   +1 more source

Theoretical modelling of the effect of plasticity on reverse transformation in superelastic shape memory alloys [PDF]

, 2003
Stimulated by recent experimental results on superelastic NiTi shape memory alloy, a theoretical study is carried out to quantify the effect of plasticity on stress-induced martensite transformation, using a constitutive model that combines phase ...
Wang, Chun Hui, Yan, Wenyi, Mai, Yiu-Wing, Zhang, Xin Ping   +3 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Thermomechanical and fire performance of DGEBA based shape memory polymer composites for constructions

, 2021
Smart shape memory polymers (SMPs) and their fibre reinforced composites have a unique ability to memorize and recover a defined shape when exposed to an external stimulus.
Herath, H. M. C. M., Epaarachchi, J. A., Emmanuel, K. D. C., Jeewantha, L. H. J., Aravinthan, T.   +4 more
core   +1 more source