Results 81 to 90 of about 796,752 (353)

Light-, pH- and thermal-responsive hydrogels with the triple-shape memory effect

, 2016
Light-, pH- and thermal-responsive hydrogels were prepared by introducing dansyl-aggregations and azo-cyclodextrin inclusion complexes as switches.
Kang, Y, Gong, XL, Li, BJ, Zhang, S, Li, BJ (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China., Jiang, ZC, Zhang, S (reprint author), Sichuan Univ, Polymer Res Inst, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China., Xiao, YY   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Effect of Solution Treatment on the Shape Memory Functions of (TiZrHf)₅₀Ni₂₅Co₁₀Cu₁₅ High Entropy Shape Memory Alloy

Entropy, 2019
This study investigated the effects of solution treatment at 1000 °C on the transformation behaviors, microstructure, and shape memory functions of a novel (TiZrHf)50Ni25Co10Cu15 high entropy shape memory alloy (HESMA). The solution treatment caused
Hao-Chen Lee, Yue-Jin Chen, Chih-Hsuan Chen   +2 more
doaj   +1 more source

A shape memory alloy adaptive tuned vibration absorber: design and implementation

, 2005
In this paper a tuned vibration absorber (TVA) is realized using shape memory alloy (SMA) elements. The elastic modulus of SMA changes with temperature and this effect is exploited to develop a continuously tunable device.A TVA with beam elements is ...
Brennan, M.J., Mace, B.R., Rustighi, E.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

X-Ray Diffraction Study of the Reverse Martensitic Transformation In Cu-Al-Ni Shape Memory Alloy

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2008
The paper presents an X ray diffraction study for a cooper based shape memory alloy. The behavior of CuAl13Ni4 alloy, which exhibits a peculiar property, is evaluated by structural changes.
Carmela GURAU, Gheorghe GURAU, F. M. Braz FERNANDES   +2 more
doaj  

Shape Memory Alloys (Part II): Classification, Production and Application [PDF]

Kemija u Industriji, 2014
Shape memory alloys (SMAs) have been extensively investigated because of their unique shape memory behaviour, i.e. their ability to recover their original shape they had before deformation.
I. Ivanic, M. Gojic, S. Kozuh
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of short heat treatment on mechanical properties and shape memory properties of Cu–Al–Ni shape memory alloy

Open Engineering
The transformation of shape-memory alloys to high-temperature shape-memory alloys can be achieved through either the addition of alloying elements or heat treatment.
Adnan Raad Suhail Ahmed, Annon Iman Adnan, Noori Sundus M., Dauod Dauod Selman   +3 more
doaj   +1 more source