Results 41 to 50 of about 3,797,196 (253)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Shape-memory surfaces for cell mechanobiology
Science and Technology of Advanced Materials, 2015 Shape-memory polymers (SMPs) are a new class of smart materials, which have the capability to change from a temporary shape ‘A’ to a memorized permanent shape ‘B’ upon application of an external stimulus.
Mitsuhiro Ebara
doaj +1 more source
Molecules, 2017 The presented paper concerns scientific research on processing a poly(lactide-co-glycolide-co-trimethylene carbonate) copolymer (PLLAGLTMC) with thermally induced shape memory and a transition temperature around human body temperature.
Joanna Walczak +2 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Shape memory polymers : the wave of the future or a passing fad? [PDF]
, 2013 textNew materials always have the possibility of revolutionizing manufacturing processes and the way we live. Bronze, steel alloys, vulcanized rubber, ceramics, and fiber optic cables are just of few of the materials man has discovered which improved ...
Sunday, Eugene Patrick
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Bounce Back, Shape-Memory Polymers [PDF]
, 2023 Shape-memory polymers are a type of polymer with a very special detail about them; they can be programed to remember a particular shape. This “programming” can be done through several different methods by adding outside stimuli (such as heat or light ...
Maldonado, Sophia, Melendez, Victoria
core +1 more source
"Research progress in use of dynamic vulcanization blends as heat?鄄triggered shape memory materials"
Hecheng xiangjiao gongyeCompared with traditional shape memory polymers, dynamic vulcanization blends used as thermally induced shape memory materials exhibited advantages such as easily tunable shape memory properties and simple preparation methods.
CHEN Liheng, XU Mengmeng, HAN Qingzhen, ZHANG Hongyu, ZHOU Huibin, ZONG Chengzhong
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Active disassembly applied to end of life vehicles [PDF]
, 2003 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Active Disassembly is technology that has been developed to allow assemblies to readily separate for recycling when they are exposed to certain triggering ...
Jones, Nicholas
core +6 more sources