Results 191 to 200 of about 264,907 (315)

Shape optimization and mechanical properties analysis of the free-form surface. [PDF]

Sci Rep
Guoyong C, Changyu C.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

High-Fidelity Optimization Framework for Helicopter Rotors

, 2009
An optimization framework for helicopter rotors based on high-fidelity coupled CFD/CSM analyses is presented. For this purpose the optimization software DAKOTA has been linked to a parametric geometry unit, a mesh generation unit and a fluid-structure ...
Imiela, Manfred
core  

A Computational Multiscale Framework for Bone Remodeling: Coupling Apparent Density Evolution and Microscale Shape Optimization. [PDF]

Int J Numer Method Biomed Eng
Vemparala B, Ji M, Mageswaran P, Knapik GG, Dibs K, Blakaj DM, Bourekas EC, Mendel E, Marras WS, Soghrati S.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Two-Phase Material Shape Optimization of an Additively Manufactured Integrated Metal and Ceramic Resin Implant-Supported Dental Crown. [PDF]

Int J Numer Method Biomed Eng
Way J, Joshi S.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Engineering oriented shape optimization of GHT-Bézier developable surfaces using a meta heuristic approach with CAD/CAM applications. [PDF]

Sci Rep
BiBi S, Misro MY, Abbas M, Birhanu A, Miura KT, Wahab MNA, Mahmoud EE.   +6 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Shape optimization of geometrically nonlinear modal coupling coefficients: an application to MEMS gyroscopes. [PDF]

Sci Rep
Schiwietz D, Hörsting M, Weig EM, Wenzel M, Degenfeld-Schonburg P.   +4 more
europepmc   +1 more source