Results 91 to 100 of about 3,793,481 (295)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Bayesian Vision for Shape Recovery [PDF]
We present a new Bayesian vision technique that aims at recovering a shape from two or more noisy observations taken under similar lighting conditions. The shape is parametrized by a piecewise linear height field, textured by a piecewise linear irradiance field, and we assume Gaussian Markovian priors for both shape vertices and irradiance variables ...
openaire +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Laser line shape recovery system based on a double pixelated axilens [PDF]
We describe a scanning system for shape recovery that employs a pair of one-dimensional interlaced axilenses encoded onto a reflective liquid-crystal spatial light modulator. The design of these axilenses with opposite depth presets allows the generation
VICTOR MANUEL ARRIZON PEÑA
core
Excellent self-recovery is critically important for soft materials such as hydrogels and shape memory polymers. In this work, weak-polyelectrolyte-based hydrogels with high mechanical strength, toughness, healability, and excellent self-recovery are ...
Xu Fang +3 more
core +3 more sources
4D printing extends additive manufacturing by introducing time-dependent functionality through stimuli-responsive feedstocks such as shape-memory polymers (SMPs).
Ayhan Hacıoğlu +2 more
doaj +1 more source
Prolonged recovery of 3D printed, photo-cured polylactide shape memory polymer networks
Shape memory polymers are materials that are able to retain a deformed state until an external stimulus, most typically heat, triggers recovery to the original geometry.
Alberto Di Bartolo, Ferry P. W. Melchels
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source

