Results 101 to 110 of about 1,675,077 (286)

Spinning Loop Black Holes

open access: yes, 2010
In this paper we construct four Kerr-like spacetimes starting from the loop black hole Schwarzschild solutions (LBH) and applying the Newman-Janis transformation.
Alesci E   +35 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Shape transformation using variational implicit functions

open access: yesProceedings of the 26th annual conference on Computer graphics and interactive techniques - SIGGRAPH '99, 1999
Traditionally, shape transformation using implicit functions is performed in two distinct steps: 1) creating two implicit functions, and 2) interpolating between these two functions. We present a new shape transformation method that combines these two tasks into a single step. We create a transformation between two N-dimensional objects by casting this
Turk, Greg, O'Brien, James F
openaire   +6 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Operator Transformations Between Exactly Solvable Potentials and Their Lie Group Generators

open access: yes, 1996
One may obtain, using operator transformations, algebraic relations between the Fourier transforms of the causal propagators of different exactly solvable potentials. These relations are derived for the shape invariant potentials.
Andrew J Bordner   +12 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Influence of surface tension on the conical miniscus of a magnetic fluid in the field of a current-carrying wire [PDF]

open access: yes, 2006
We study the influence of surface tension on the shape of the conical miniscus built up by a magnetic fluid surrounding a current-carrying wire. Minimization of the total energy of the system leads to a singular second order boundary value problem for ...
Engel, Andreas   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Study the effects of residual B19' phase on the phase transformation in shape memory NiTi alloys fabricated by laser powder bed fusion

open access: yesJournal of Materials Research and Technology
The shape memory effect of near-equiatomic Ni–Ti shape memory alloys (SMAs) fabricated via laser powder bed fusion (LPBF) is attributed to the diffusionless phase transformation between austenite (B2) and martensite (B19').
Shenyue Zhou   +4 more
doaj   +1 more source

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