Results 111 to 120 of about 1,675,077 (286)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Numerical Model For Vibration Damping Resulting From the First Order Phase Transformations
A numerical model is constructed for modelling macroscale damping effects induced by the first order martensite phase transformations in a shape memory alloy rod.
Melnik, Roderick V. N. +1 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Supporting reinterpretation in computer-aided conceptual design [PDF]
This paper presents research that aims to inform the development of computational tools that better support design exploration and idea transformation - key objectives in conceptual design.
AHRC (Funder) +7 more
core
FtsZ‐Induced Shape Transformation of Coacervates
AbstractRecently, both the cellular and synthetic biology communities have expressed a strong interest in coacervates, membrane‐less liquid droplets composed of densely packed multivalent molecules that form as a result of spontaneous phase separation.
Federico Fanalista +4 more
openaire +4 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Implementation of the harmonic transformation method in shape optimization
The paper describes an implementation of the variant of the speed method in shape optimization for plane elastic structures, based on harmonic transformations.
Antoni Żochowski
doaj
Learning shape-to-shape transformation
Many problems in computer graphics and geometric modeling, e.g., skeletonization, surface completion, and shape style transfer, can be posed as a problem of shape-to-shape transformation. In this thesis, we are interested in learning general-purpose shape transform, e.g., between 3D objects and their skeletons, between chairs and tables, and between ...
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
β-Ti shape-memory alloys, that show shape-memory effect or superelasticity owing to thermoelastic martensitic transformation, have potential for various applications.
Yuxin Song +3 more
doaj +1 more source

