Results 41 to 50 of about 57,136 (306)

Analytical models for high performance milling. Part I: cutting forces, structural deformations and tolerance integrity [PDF]

open access: yes, 2006
Milling is one of the most common manufacturing processes in industry. Despite recent advances in machining technology, productivity in milling is usually reduced due to the process limitations such as high cutting forces and stability.
Budak, Erhan
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cutting of Siliceous Dolomite by Special-Shaped PDC Cutter under Confining Pressure

open access: yesShiyou jixie
The dolomite formation is an important field for oil and gas exploration in the future. However, due to the high confining pressure environment in wellbore and the hard-to-drill characteristics of dolomite, traditional planar cutter PDC bit is prone to ...
Tian Wanqing   +5 more
doaj   +1 more source

Prediction of wear life of shield disc cutter in complex formations based on genetic programming

open access: yesGong-kuang zidonghua, 2018
In process of shield tunneling in complex formation, wear of disc cutter is extremely serious and service life is hard to predict, and influence factors of the disc cutter wear are multi-dimensional and uncertain.
QIAO Jinli   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Calculation of the parameters for disc saws that use method of running for toolmaking with uneven tooth pitch [PDF]

open access: yes, 2014
Розглянуто особливості розрахунку кутового кроку зубів інструменту другого порядку, а так само їх розташування, для обробки заготовок з нерівномірним кроком зубів.
Parnenko, V., Парненко, В. С.
core  

Rapid design of tool-wear condition monitoring systems for turning processes using novelty detection [PDF]

open access: yes, 2009
Condition monitoring systems of manufacturing processes have been recognised in recent years as one of the key technologies that provide the competitive advantage in many manufacturing environments. It is capable of providing an essential means to reduce
Al-Azmi, A, Al-Habaibeh, A, Redgate, J
core   +1 more source

Analysis of the Geometric Shape of the Cutter in Ring-core Measurement

open access: yesProcedia Engineering, 2014
AbstractEstimation of the magnitude, sense and direction of the residual stress components in mechanical parts is a key factor for its lifespan and safety prediction. The principles of the semi-destructive Ring-Core method for residual stress determination are already well known. Commercially available measuring systems now enables to connect numerical
Menda, František   +3 more
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Hole cutter [PDF]

open access: yes, 1975
An adjustable hole cutter is described for use in forming circular openings in workpieces. The hole cutter is characterized by a mount of a substantially planar configuration, positionable into a plane paralleling the working plane of a selected ...
Newby, D. T., Thornton, G. E.
core   +1 more source

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