Results 131 to 140 of about 2,325,002 (342)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Decision-making by children [PDF]

, 2007
In this paper, we examine the determinants of decision-making power by children and young adolescents. Moving beyond previous economic models that treat children as goods consumed by adults rather than agents, we develop a noncooperative model of ...
Lundberg, Shelly, Romich, Jennifer, Tsang, Kwok P.   +2 more
core   +1 more source

COVID-19 in Women's health: Pre-operative gynaecological assessment and shared decision making

, 2021
Elizabeth Ball, Fredric Willmott, Carol Rivas, Chiraag Talati   +3 more
openalex   +2 more sources

The Role of Shared Decision-Making in Personalised Medicine: Opening the Debate [PDF]

, 2022
Héctor Guadalajara, Olatz López-Fernández, Miguel León Arellano, Víctor Domínguez-Prieto, Cristina Caramés, Damián García‐Olmo   +5 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Effects of patient decision aids used pre-consult or in-consult on patient-clinician communication - secondary analysis of a systematic review with meta-analysis

BMC Medical Informatics and Decision Making
Background Patient decision aids (PtDAs) provide benefits and risks of options for a specific decision, and help patients clarify their values. This study examined whether the timing of PtDA use—before (pre-consult) or during (in-consult) the clinical ...
Bettina Mølri Knudsen, Stine Rauff Søndergaard, Meg Carley, Karina Dahl Steffensen, Dawn Stacey   +4 more
doaj   +1 more source

Improving Patient Decision-Making in Health Care [PDF]

, 2011
Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman, Elliott S. Fisher, John E. Wennberg, Julie P. W. Bynum, Michael J. Barry, Shannon Brownlee   +5 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Integrating Public Health Ethics into Shared Decision Making for Children During the Novel Coronavirus Disease-19 Pandemic [PDF]

, 2020
Angira Patel, Dalia M. Feltman, Erin Paquette   +2 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source