Results 141 to 150 of about 2,204,503 (352)

Recommendations for Preoperative Assessment and Shared Decision-Making in Cardiac Surgery

, 2020
Purpose of Review Recommendations about shared decision-making and guidelines on preoperative evaluation of patients undergoing non-cardiac surgery are abundant, but respective recommendations for cardiac surgery are sparse. We provide an overview of
Stueber, Frank, Mihalj, Maks, Carrel, Thierry, Luedi, Markus M., Urman, Richard D.   +4 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Purposeful SDM: A problem-based approach to caring for patients with shared decision making

Patient Education and Counseling, 2019
Objective Patient involvement focused the growth of Shared Decision Making (SDM) in contemporary healthcare practice, research, and education. Whilst important, securing appropriate patient involvement or equipping patients to choose is not necessarily ...
Ian G Hargraves, V. Montori, J. Brito, Marleen Kunneman, Kevin Shaw, C. LaVecchia, Michael E. Wilson, L. Walker, Bjorg Thorsteinsdottir   +8 more
semanticscholar   +1 more source

Shared decision making in psychiatric practice and the primary care setting is unique, as measured using a 9-item Shared Decision Making Questionnaire (SDM-Q-9)

, 2013
Carlos De las Cuevas,1,2 Wenceslao Peñate,3 Lilisbeth Perestelo-Pérez,2,4 Pedro Serrano-Aguilar2,41Department of Psychiatry, University of La Laguna, Tenerife, Spain; 2Health Services Research Network for Chronic Diseases (REDISSEC ...
Perestelo-Pérez L, Serrano-Aguilar P, De las Cuevas C, Peñate W   +3 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Shared Decision Making in Prostate-Specific Antigen Testing

Journal of Primary Care & Community Health, 2013
Introduction and aims: Professional societies recommend that the decision to screen for prostate cancer involves a shared discussion between patient and provider. Many men are tested without this discussion.
Alison R. Landrey, Daniel D. Matlock, Laura Andrews, Michael Bronsert, Tom Denberg   +4 more
doaj   +1 more source

Randomised controlled trial of an interactive multimedia decision aid on benign prostatic hypertrophy in primary care [PDF]

, 2001
Objective To determine whether a decision aid on benign prostatic hypertrophy influences decision making, health outcomes, and resource use.Design Randomised controlled trial.Setting 33 general practices in the United Kingdom.Participants 112 men with ...
Davis, H, Haines, A, Coulter, A, Gray, A, Murray, E, Tai, SS   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Shared decision-making equals empowerment : portraits of teacher-leaders in a high school setting [PDF]

, 1989
The purpose of this study was to reveal a consciousness of empowerment of three teacher-leaders who participated in the life of their school beyond their own classroom walls.
Scroggs, Richard Wilcher, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core