Results 171 to 180 of about 54,330 (258)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Revealing differential psychotic symptoms in schizophrenia and bipolar I disorder by manifold learning and network analyses. [PDF]

Transl Psychiatry
Kim YH, Jang J, Kang N, Jeong JH, Kim J, Ahn YM, Kim YS, Kim SH.   +7 more
europepmc   +1 more source

Advancing Quantitative Susceptibility Mapping With 2.5D Diffusion Models for Rapid Intracranial Hemorrhage Quantification

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a generative diffusion model‐based approach for robust and efficient quantitative susceptibility mapping (QSM) reconstruction in intracranial hemorrhage (ICH), applicable to both standard gradient echo (GRE) and rapid echo planar imaging (EPI) acquisitions.
Zhuang Xiong, Yang Gao, Feng Liu, Derek Emery, Ken Butcher, Alan H. Wilman, Hongfu Sun   +6 more
wiley   +1 more source

VQ‐Wave: A Physics‐Driven Spatiotemporal Deep Learning Approach for Noncontrast‐Enhanced Lung Ventilation and Perfusion MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman, Pavlos Panos, Philipp Latzin, Oliver Bieri   +3 more
wiley   +1 more source

Targeting macrophages in OA nanomedicine: Therapeutic opportunity or delivery delusion? A pragmatic reappraisal. [PDF]

Asian J Pharm Sci
Yao Q, Fu B, Kou L.
europepmc   +1 more source

Assessing ChatGPT for taxonomic and floristic studies

Nordic Journal of Botany, EarlyView.
The advancement of biological sciences has long been closely linked to technological progress. ChatGPT, a generative artificial intelligence chatbot capable of producing human‐like conversational responses, has recently attracted attention as a potential support tool for scientific research.
Mykyta Peregrym, Olena Kozak, Ahmet Emre Yaprak, Alan Elliott, Pedro Bond Schwartsburd, Karime Abidkulova, Anna Voytsekhovich, Olena Danylevska   +7 more
wiley   +1 more source

Clinical Applications of Multimodal Artificial Intelligence in Otolaryngology: A State‐of‐the‐Art Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Artificial intelligence (AI) has advanced to simultaneously process visual, auditory, and textual inputs, providing users with “multimodal” AI. Given the clinical integration potential of these tools, otolaryngologists must stay informed. This study reviews current literature on applications of multimodal AI in otolaryngology.
Ying Jie Li, Flora Su, Norbert Banyi, Philip Edgcumbe, Andrew Thamboo, Ameen Amanian   +5 more
wiley   +1 more source

Delusion-like thinking is associated with lower individual alpha peak frequency. [PDF]

Schizophrenia (Heidelb)
Tarasi L, Romanazzi D, Pasini A, Romei V.   +3 more
europepmc   +1 more source

Rehabilitation needs of long COVID patients in British Columbia

PM&R, EarlyView.
Abstract Introduction COVID‐19 can result in persistent symptoms and functional impairment that significantly impact daily functioning, highlighting the need for targeted rehabilitation. However, there is a lack of data on what proportion of long COVID patients need rehabilitation and which types are required.
Débora M. Petry Moecke, Evan H. Kwong, Sonya Cressman, Jennifer Yao, Chiara Singh, Carolyn Taylor, Pat G. Camp   +6 more
wiley   +1 more source

Ethical and Communicative Challenges in Informing Patients with Delusional Infestation: Insights from Moral Case Deliberation. [PDF]

Acta Derm Venereol
Kemperman PMJH, Saradjzada V, Vulink NCC, De Rie MA, Voskes Y.   +4 more
europepmc   +1 more source