Results 71 to 80 of about 104,236 (292)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pengaruh Credibility of Shared Experience dan Information Usefulness Terhadap Purchase Intention Melalui Adoption of Shared Experience Sebagai Mediator (Studi Kasus pada Traveloka) [PDF]
, 2018 Penelitian ini bertujuan untuk mengetahui peran adoption of shared experience sebagai mediator terhadap credibility of shared experience, information usefulness dan purchase intention pada pelanggan Traveloka, serta mengetahui seberapa besar pengaruh ...
INDAH KURNIA
core
Shared Intention is Not Joint Commitment
Journal of Ethics and Social Philosophy, 2018 Abstract here.
Kopec, Matthew, Miller, Seumas
openaire +4 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Impact of big five personality traits on behavioral intention to participate in smart shared parking
KSCE Journal of Civil EngineeringThe rapid growth of peer-to-peer sharing economy services has given rise to the concept of prosumers, individuals participating as both service users and providers.
Doosun Hong
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Transformational and shared leadership relationships with employee performance and intention to leave among IT knowledge workers: mediating effects of communication quality and organizational commitment [PDF]
Central European Management JournalPurposeThis study investigates the role of transformational and shared leadership in relation to employee performance and intention to leave. Moreover, the indirect effects of communication quality and organizational commitment on these relationships ...
Agnieszka Zielińska +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Cooperative activity, shared intention, and exploitation
Jules Salomone-Sehr argues that an activity is cooperative if and only if, roughly, it consists of several participants’ actions that are (i) coordinated for a common purpose (ii) in ways that do not undermine any participant’s agency.
Blomberg, Olle,, Malmqvist, Erik,
core +1 more source