Results 51 to 60 of about 752,131 (343)
Shared Autonomous Mobility Services Show Promise for Increasing Access to Employment in Southern California [PDF]
, 2020 Workers in Southern California currently face transportationrelated challenges accessing employment opportunities, including but not limited to high parking costs and/or limited parking availability in dense employment and residential areas; long commute
Ahmed, Tanjeeb +4 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Mobile Intermediaries Supporting Information Sharing between Mobile Users [PDF]
, 2002 Mobile device's networking capabilities offer opportunities for a new range of applications. We consider here a service that allows mobile users taking part in virtual meeting rooms to share information and documents. The sharing is promoted by a recommender system that assists users browsing documents, by making recommendations in the form of URLs ...
Norliza Zaini,, Moreau, Luc
openaire +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Can the co-existence of bike, e-scooter, and car-sharing promote sustainable mode choices?
Sustainable FuturesThe introduction of shared mobility systems has received attention as a potential measure to reduce private car use and tackle the environmental and social externalities of urban mobility.
Roxani Gkavra +2 more
doaj +1 more source
Balancing Affordability and Opportunity: An Evaluation of Affordable Homeownership Programs With Long-Term Affordability Controls [PDF]
, 2010 Examines seven shared equity programs that allow low-income families to purchase homes at below-market prices with resale restrictions and their outcomes in terms of preserving affordability, personal wealth creation, security of tenure, and ...
Brett Theodos +2 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Transportation Research Interdisciplinary Perspectives, 2020 The current mobility system faces severe sustainability challenges and requires a fundamental change. Enabled by smart mobility innovations, the previously separate fields of shared, electric, and automated mobility seem to converge into a promising ...
Tanja Manders +3 more
doaj +1 more source
Simulating shared mobility in Helsinki [PDF]
, 2017 Replacing private car travel with fleets of shared vehicles cuts emissions, decreases congestion and frees public space, writes Francisco ...
Furtado, Francisco
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source