Results 221 to 230 of about 205,713 (312)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Nothing About Us Without Us in the First 1000 Days: Developing Inclusive Early Years Support With Disabled Families. [PDF]

Sociol Health Illn
Beckett AE, McLean N, Miller A, Heaton R, Borisova D.   +4 more
europepmc   +1 more source

Parenting Early Intervention Programme Evaluation (Research report DFE-RR121(a)) [PDF]

, 2011
Band, Sue, Barlow, Jane, Conlon, Gavan, Cullen, Mairi Ann, Cullen, Stephen, Davis, Hilton, Evans, Ray, Lindsay, Geoff, Strand, Steve   +8 more
core  

Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis

Advanced Science, EarlyView.
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan, Yunping Chen, Wei Zhou, Yanghong Xu, Junran Huang, Yi Chen, Jizhou Meng, Guoxin Yao, Wenchao Huang   +8 more
wiley   +1 more source

Using Co-Design to Adapt a Digital Parenting Program for Parents Seeking Mental Health Support. [PDF]

Children (Basel)
Bennett ML, Wu L, Seguin JP, Olivier P, Reupert A, Jorm AF, Grant S, Vaxevanis H, Li M, Xie J, Yap MBH.   +10 more
europepmc   +1 more source

Redefining the Health Risk of Battery Materials Through a Biologically Transformed Metal Mixture

Advanced Science, EarlyView.
Inhaled NCM particles undergo lysosomal degradation, releasing complex ion mixtures that induce systemic impact. The impact is determined by a critical balance between antagonistic Ni‐Co interactions and synergistic Mn effects. To capture these complexities in risk assessment, we develop an IAI model, ensuring a more accurate quantitative risk ...
Ze Zhang, Gan Miao, Xueyu Zhang, Zhao Shu, Dawei Lu, Yujie Song, Shanfa Yu, Qian Liu, Yang Song, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

Effects of grandparents' involvement on young children's resilience: mother's parenting stress and family strength as mediators. [PDF]

Psicol Reflex Crit
Wu J, Zhu J, Lei Y, Shi L.
europepmc   +1 more source

High expectations, high support and high challenge: Protecting children more effectively through better support for front-line social work practice [PDF]

, 2012

core  

Electro‐Chemo‐Mechanical Coupling in Composite Cathodes of Sulfide‐Based All‐Solid‐State Batteries: Pathways, Degradation, and Design Rules

Advanced Science, EarlyView.
This review provides an integrated framework for achieving superior electrochemical performance in sulfide‐based all‐solid‐state batteries. It first delineates mechano‐electrochemical failure modes of cathode active materials and solid electrolytes, then outlines engineering principles for particle morphology, electronic and ionic conduction, and ...
Gawon Song, Seonghyun Lee, Minseon Lee, Junsung Park, Kyu Tae Lee   +4 more
wiley   +1 more source

Understanding the Interplay Between Thermal Activation, Diffusion, and Phase Segregation of Molecular Dopants Blended with Polymeric Semiconductors

Advanced Electronic Materials, EarlyView.
The use of air stable but thermally labile molecules provides an efficient strategy for the N‐type doping of organic semiconductors with relatively low electron affinities. Design criteria for efficient dopants should also take into account diffusion and phase segregation that cannot be decoupled from thermally activated doping.
Francesca Pallini, Sara Mattiello, Mauro Sassi, Gabriele Paoli, Giuseppe Mattioli, Pietro Rossi, Giulia Coco, Alberto D. Scaccabarozzi, Brian Minki Kim, Pietro Mariani, Hiba Wakidi, Sadie M. Flagg, Massimiliano D'Arienzo, Mario Caironi, Thuc‐Quyen Nguyen, Luca Beverina   +15 more
wiley   +1 more source