Results 61 to 70 of about 205,713 (312)

A review of training and materials which aim to support the children's workforce to reduce the impact of childhood poverty and disadvantage [PDF]

open access: yes, 2010
The Children’s Workforce Development Council (CWDC) commissioned DMSS Research and Consultancy to undertake a review of national and local support, guidance and training that aims to equip the children’s workforce to reduce the impact of child poverty ...

core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

A darn good hiding or the naughty step? : ideas on child discipline in New Zealand 1890-2008 : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in History at Massey University [PDF]

open access: yes, 2008
This thesis examines the history of child discipline in New Zealand since 1890, taking into account both trends in child-rearing advice and the common practices of ordinary parents.
Rayner, Helen J
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

The Association Between Marital Power and Adolescents’ Social Adjustment: The Mediating Role of Co-Parenting

open access: yesSAGE Open
This study investigated how marital power influence adolescents’ social adjustment in China, based on a sample of 759 middle school students. While prior research has largely focused on marital relationships and co-parenting, few studies have examined ...
Ying Wang   +3 more
doaj   +1 more source

Modeling the Relationships Between Parent Strengths, Parenting Efficacy Beliefs, and Child Social-Emotional Behavior

open access: yesInternational Journal of Child Development and Mental Health, 2020
The purpose of the study was to evaluate the relationships between child participation in parent interest-based and parent ability-based everyday activities, parenting efficacy beliefs, and child well-being.
Carl Joseph Dunst
doaj  

SHARED PARENTING IN FRAGILE FAMILIES [PDF]

open access: yes
This paper uses data from the Fragile Families and Child Wellbeing Study to examine the frequency of parent-child interaction in several areas across a range of family types.
Marcia Carlson, Sara McLanahan
core  

Temperament influences on parenting and child psychopathology: Socio-economic disadvantage as moderator [PDF]

open access: yes, 2008
Despite calls for research on how the socio-economic environment may be related to temperament we still do not know enough about the relationship between temperament and socio-economic disadvantage (SED).
Flouri, Eirini
core   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Parenting for sustainability: a moderated mediation study on adolescent purchase intentions

open access: yesInternational Journal of Adolescence and Youth
Despite rising interest in sustainable fashion in India, little is known about how parental factors shape adolescents’ sustainable purchase intentions—particularly within urban, educated Indian families. This study explores how parental factors influence
Kavitha Venkatasubramany Iyer   +1 more
doaj   +1 more source

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