Results 161 to 170 of about 94,692 (282)

Perspective: Depression in Persons with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Depression is a prevalent and disabling syndrome characterized by sustained sadness and/or anhedonia, as well as cognitive and physical symptoms. In Parkinson's disease (PD), depression is both common and clinically challenging due to overlapping symptoms and complex etiologic interactions. Major depressive disorder occurs in approximately 17%
Albert F.G. Leentjens, Gregory M. Pontone   +1 more
wiley   +1 more source

Rehabilitation needs of long COVID patients in British Columbia

PM&R, EarlyView.
Abstract Introduction COVID‐19 can result in persistent symptoms and functional impairment that significantly impact daily functioning, highlighting the need for targeted rehabilitation. However, there is a lack of data on what proportion of long COVID patients need rehabilitation and which types are required.
Débora M. Petry Moecke, Evan H. Kwong, Sonya Cressman, Jennifer Yao, Chiara Singh, Carolyn Taylor, Pat G. Camp   +6 more
wiley   +1 more source

TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia

CNS Neuroscience &Therapeutics, EarlyView., 2023
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi, Decheng Ren, Fan Yuan, Zhou Zhang, Daizhan Zhou, Xin Yi, Lei Ji, Keyi Li, Fengping Yang, Xi Wu, Xingwang Li, Yifeng Xu, Yun Liu, Peng Wang, Changqun Cai, Chuanxin Liu, Qian Ma, Lin He, Yi Shi, Guang He   +19 more
wiley   +1 more source

Looking at Us Through Their Eyes. The Analytical Process from Ethnographic Perspectives1

Journal of Analytical Psychology, EarlyView.
Abstract This article looks at the analytical situation through the Others’ eyes—through examples from contemporary ethnographies of foreign cultures. It discusses the following issues: a) The analogy between the ontological worlds of the dead, ghosts, animals and dreams in “primitive populations” and the analytical psychological descriptions of the ...
Stefano Carta
wiley   +1 more source

Long‐term regular follow‐up yields important benefits in forensic psychiatric patients with psychosis: A 2‐year longitudinal study on psychopathology, general health, quality of life, and functioning

Journal of Forensic Sciences, EarlyView.
Abstract Forensic psychiatric patients often present with severe psychopathology, functional impairment, and poor quality of life. Longitudinal follow‐up studies in forensic psychiatric outpatient populations remain limited. The objective is to assess psychopathology, quality of life, global functioning, and general health in forensic psychiatric ...
Panagiota Bali, Maria Markopoulou, Phoebe Douzenis, Konstantinos Tasios, Emmanouil Rizos, Ioannis Michopoulos, Athanasios Douzenis   +6 more
wiley   +1 more source

Pineal Gland Volume, Sleep Quality, and Psychiatric Disorders: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Disturbances in sleep and circadian rhythms are features of several psychiatric disorders. The pineal gland regulates these rhythms via melatonin, with pineal gland volume (PGV) serving as a structural proxy. We conducted a meta‐analysis to synthesize evidence on differences in PGV between patients with psychiatric disorders and ...
Sophie Bolwig, Kristian H. R. Jensen
wiley   +1 more source

Effectiveness of a Psychiatrist‐Led Clinic for Metabolic Health in Severe Mental Illness: A Retrospective Chart Review Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios, Femin Prasad, Riddhita De, Kateryna Maksyutynska, Akash PrasannaKumar, Vittal Korann, Tariq Ahmed, Marcos Sanches, Leah Burton, Mohammed A. Alarabi, Tanner Isinger, Michelle Desanti, Rebecca Oliveira, Daphne J. Korczak, Ariel Graff‐Guerrero, Gary Remington, Margaret K. Hahn, Sri Mahavir Agarwal   +17 more
wiley   +1 more source

Trans-Ancestry Analysis of Psychosis Biotypes: Shared Polygenic Risk and Unique Genomic Associations

Abstract The Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) has categorized psychosis disorders (Schizophrenia, Schizoaffective Disorder and Bipolar Disorder) into three distinct Biotypes, based on neurobiological measurements in a multi-ancestry sample.
Elliot Gershon, Cuihua Xia, Ney Alliey-Rodriguez, Carol Tamminga, Matcheri Keshavan, Godfrey Pearlson, Sarah Keedy, David Parker, Rebekka Lencer, Scot Hill, Jeffrey Bishop, Michael Gandal, Cindy Wen, Rujia Dai, Chao Chen, Chunyu Liu   +15 more
openaire   +1 more source

Comparative Clinical Trajectories Across Cannabis‐Related and Nonsubstance‐Related Psychoses

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Research indicates that first‐episode psychosis (FEP) with cannabis use disorder (CUD) carries a substantial disease burden, but more granular clinical trajectories of cannabis‐related psychoses remain unclear. This study examines the clinical trajectories of first clinically diagnosed FEP&CUD and cannabis‐induced psychosis (CIP) in
Antti Mustonen, Solja Niemelä, Alexander Denissoff, Antti Tanskanen, Ellenor Mittendorfer‐Rutz, Markku Lähteenvuo, Jari Tiihonen, Heidi Taipale   +7 more
wiley   +1 more source

The Effect of Benzodiazepines on Catatonia: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Catatonia is a complex psychomotor syndrome associated with various psychiatric and somatic underlying disorders. Current treatment protocols include benzodiazepines and electroconvulsive therapy (ECT). Despite their widespread use, systematic evidence regarding efficacy and optimal benzodiazepine dosage remains limited.
L. Bot, B. Schotsman, E. Oostra, A. W. Hoogendoorn, B. W. C. Storosum, C. H. M. Planting, H. M. Heller, J. J. B. van der Vlugt, J. G. van Mill, L. J. C. A. Smarius, M. S. Oudijn, M. S. van Noorden, S. M. M. Lange, Y. D. van der Werf, E. van Exel   +14 more
wiley   +1 more source