Results 101 to 110 of about 390,971 (306)

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Cosmic Shear Results from the Deep Lens Survey - II: Full Cosmological Parameter Constraints from Tomography

, 2016
We present a tomographic cosmic shear study from the Deep Lens Survey (DLS), which, providing a limiting magnitude r_{lim}~27 (5 sigma), is designed as a pre-cursor Large Synoptic Survey Telescope (LSST) survey with an emphasis on depth.
Hilbert, Stefan, Jee, M. James, Schmidt, Samuel, Schneider, Michael D., Tyson, J. Anthony, Wittman, David   +5 more
core   +2 more sources

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Shear Analogy Stiffness Adjustment for CLT Plates

BioResources
In serviceability limit state, one-dimensional approaches are commonly used to estimate the bending stiffness and vertical displacement of cross-laminated timber (CLT) panels, such as the shear analogy method combined with mechanics of materials ...
Guilherme dos Santos Silva, Fabrício da Silva Aguiar, Elvys Dias Reis, Herisson Ferreira dos Santos, Emerson Faustino, Adriano Reis Prazeres Mascarenhas, André Luis Christoforo   +6 more
doaj  

Buckling and free vibration analysis of orthotropic plates by using exponential shear deformation theory

Latin American Journal of Solids and Structures
In the present paper, an exponential shear deformation theory is used to determine the natural frequencies and critical buckling loads of orthotropic plates.
A. S. Sayyad, Y. M. Ghugal
doaj   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Analysis of Static Bending of Plates FGM Using Refined High Order Shear Deformation Theory

Journal of Building Materials and Structures, 2019
This work deals with the analysis of the mechanical bending behavior of a rectangular plate simply supported on four sides (FGM), subjected to transverse static loading.
S. Merdaci, S. Boutaleb, H. Hellal, S. Benyoucef   +3 more
doaj   +1 more source

Cosmic shear results from the deep lens survey - I: Joint constraints on omega_m and sigma_8 with a two-dimensional analysis

, 2013
We present a cosmic shear study from the Deep Lens Survey (DLS), a deep BVRz multi-band imaging survey of five 4 sq. degree fields with two National Optical Astronomy Observatory (NOAO) 4-meter telescopes at Kitt Peak and Cerro Tololo.
Hilbert, Stefan, Jee, M. James, Schmidt, Samuel, Schneider, Michael D., Tyson, J. Anthony, Wittman, David   +5 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source