Optimizing roadway location and cross section under superposition of residual coal pillars and adjacent goafs in close distance coal seams. [PDF]
Ren Y, Li J, Li Y, Wu X, Qin H.
europepmc +1 more source
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz +3 more
wiley +1 more source
Effect of Curvature Height on the Low-Velocity Impact Behaviour of Unidirectional T300/5208 CFRP Laminated Shell Panels: A Comparative Numerical Parametric Analysis of Intralaminar + Interlaminar and Intralaminar-Only Models. [PDF]
Gök O.
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Sustainable Development Advantages of Cross-Laminated Timber (CLT) and Cross-Laminated Bamboo and Timber (CLBT). [PDF]
Li J, Zhao K.
europepmc +1 more source
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source
The free vibrational characteristic of PFGM beams near the post-buckling configuration under thermal loads. [PDF]
Lyu Q, Zhao Y, Zeng H, Mu Y.
europepmc +1 more source
Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park +5 more
wiley +1 more source
Ultrasonic Testing of Laser Welds in Medium-Thick Titanium Alloy Plates. [PDF]
Zhou C +5 more
europepmc +1 more source
Circular Innovations in Complex Systems: A Blueprint of Four Design Archetypes
ABSTRACT Circular innovations (CI), defined as the redesign of products, services or practices to minimise waste, reduce resource use and regenerate natural systems, are essential for advancing the circular economy. Despite growing recognition, their deployment in systems of linked parts with unpredictable interactions (complex systems) remains limited
Sophie Führer +2 more
wiley +1 more source

