Results 161 to 170 of about 7,472 (217)

The vertebro-subclavian artery angle modulates hemodynamic mechanisms of atherosclerosis in vertebral artery origin: a combined clinical and computational fluid dynamics study. [PDF]

Front Bioeng Biotechnol
Chen L, Hou B, Li C, Cao Y, Wang X, Liang G.   +5 more
europepmc   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

The Sun as a driver of the inner heliosphere: Modern investigations of fundamental plasma processes. [PDF]

Nat Commun
Ervin T, Nakhleh AJ, Bharati Das S.
europepmc   +1 more source

Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park, Alexander Bevacqua, Mingyang Cui, Marina Nichols, Jianzhu Chen, Jongyoon Han   +5 more
wiley   +1 more source

Approximate analytical prediction on elastic properties of Diamond structures with varying porosities and orientations. [PDF]

Front Bioeng Biotechnol
Wang H, Lyu Y, Jiang J, Zhao F, Bosiakov S, Zhu H.   +5 more
europepmc   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

Mechanobiology-based strategies for the maturation of biofabricated cartilage constructs. [PDF]

Front Bioeng Biotechnol
López-González I, Campillo N, Baena JM.   +2 more
europepmc   +1 more source

Circular Innovations in Complex Systems: A Blueprint of Four Design Archetypes

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular innovations (CI), defined as the redesign of products, services or practices to minimise waste, reduce resource use and regenerate natural systems, are essential for advancing the circular economy. Despite growing recognition, their deployment in systems of linked parts with unpredictable interactions (complex systems) remains limited
Sophie Führer, Lucas Miehé, Catharina Bening   +2 more
wiley   +1 more source

Osteosarcoma pulmonary metastasis: the hemodynamic mechanical-filtration hypothesis for subpleural predominance. [PDF]

Front Oncol
Zhang K.
europepmc   +1 more source

Infinite Functional Versatility, Formidable Limits: Evaluating Gallium‐Based Liquid Metals in Rechargeable Batteries

Carbon Energy, EarlyView.
Beyond the hype surrounding the self‐healing properties of gallium‐based liquid metals (Ga‐LMs), this perspective critically examines their functional roles in metal‐ion batteries, highlighting both their underlying merits and the often‐overlooked challenges, including non‐representative design and testing configurations, performance overestimations ...
Turly P. P. Sumanasekara, Petar Jovanović, Ali Zavabeti, Dan Yang, Mainak Majumder, Anthony F. Hollenkamp, Torben Daeneke, Mahdokht Shaibani   +7 more
wiley   +1 more source