Results 31 to 40 of about 77,538 (269)

Embedded Connector in Severe Optimization of Steel Plate for Shear Strengthening of RC Beam: Experimental and Numerical Investigations

open access: yesAdvances in Civil Engineering, 2018
Environmental impact has become one of the major factors taken into consideration for recent civil engineering studies and projects. Thus, researchers have been concentrating on shear strengthening of existing reinforced concrete structure as an upgrade ...
Md. Ashraful Alam   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Out-of-Plane Bending and Shear Behaviors of Steel Plate-Concrete Walls for Nuclear Power Plants

open access: yesAdvances in Civil Engineering, 2020
The steel plate-concrete structure, with its advantages of modular construction, good seismic capacity, and strong impact resistance, has been gradually replacing the reinforced concrete structure in the containment vessel and internal workshop structure
Zhihua Chen   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Analytical model for the load-slip relationship of bearing-shear connectors

open access: yesFrontiers in Materials, 2023
The shear behavior of shear connectors in steel-concrete composite structures mainly depends on its load-slip relationship. The load-slip relationship not only reflects the shear capacity and slip capacity of the shear connectors, but also the ...
Fengjiang Qin   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Bed Shear Stress and Near‐Bed Flow Through Sparse Arrays of Rigid Emergent Vegetation

open access: yesWater Resources Research
Vegetation is an essential component of natural rivers and has significant effects on flow and morphodynamic processes. Although progress has been made in characterizing flow resistance in vegetated flows, the impact of vegetation on bed shear stress, a ...
J. Aliaga, J. Aberle
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Elasto-plastic Buckling Analysis of Novel Origami-inspired Steel Plate Shear Wall with Two-side Connections

open access: yes工程科学与技术, 2018
Existing steel plate shear walls could not meet the requirements of high mechanical properties and energy dissipation performance at the same time. To solve this problem, based on the origami theory three kinds of novel pre-folded steel plate shear walls
Jinyu LU, Ding LU, Xudong QIAO
doaj  

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