Results 61 to 70 of about 3,769,575 (399)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Influence of Shear Motion on Evolution of Molecular Clouds in the Spiral Galaxy M51 [PDF]

open access: yes, 2013
We have investigated the dynamics of the molecular gas and the evolution of GMAs in the spiral galaxy M51 with the NRO 45-m telescope. The velocity components of the molecular gas perpendicular and parallel to the spiral arms are derived at each spiral phase from the distribution of the line-of-sight velocity of the CO gas.
arxiv   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Shear critical R/C columns under increasing axial load [PDF]

open access: yes, 2020
Structural elements in old reinforced concrete (R/C) frame buildings are often prone to shear or flexure-shear failure, which can eventually lead to loss of axial load capacity of vertical elements and initiate vertical progressive collapse of a building.
Elwood   +14 more
core   +2 more sources

A COMPREHENSIVE REVIEW OF THE LITERATURE ON SHEAR STRENGTH OF PUSH-OUT TESTS OF HEADED STUDS: Comprehensive and holistic analysis focusing on the type of slab, failure mode, and stud diameter

open access: yes, 2017
We collected push-out test results from researches, and analyzed characteristics of shear strength of headed stud from 1002 results, using headed stud diameter, types of slab, and failure modes.
Hirama Chihiro   +3 more
semanticscholar   +1 more source

THE INVESTIGATION OF THE STRENGTH REDUCTION FACTOR IN PREDICTING THE SHEAR STRENGTH

open access: yesJournal of Theoretical and Applied Mechanics, 2015
Design codes propose to restrict the nominal probability of failure within specific target structural reliability levels using a load factor and a strength reduction factor. In the current ACI318 Code, the strength reduction factor varies from 0.65 to 0.90, and the value considered in predicting the shear strength equals to 0.75.
Arslan, Guray   +2 more
openaire   +5 more sources

Derivation of the shear strength of continuous beams [PDF]

open access: yesEuropean Journal of Wood and Wood Products, 2010
The elastic--full plastic loading curve is for all materials sufficient to explain the strength of beams and beam columns loaded by bending and compression. This theory is extended for the influence of shear stress, and it is shown to be the only way to explain the combined bending-shear strength from test results. Also, the in the past derived bearing
van der Put, T.A.C.M. (author)   +1 more
openaire   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Shear strength analysis of concrete beams reinforced with GFRP bars using strut and tie model [PDF]

open access: yes, 2011
This dissertation presents an experimental investigation on the behavior and ultimate shear strength of reinforced concrete beam. Sixteen reinforced concrete beams was design and tested to failure. This study consists of two series of beams, which are
Mokhtar, Norfaniza
core  

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye   +16 more
wiley   +1 more source

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