Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
Polymer-Bonded/Bolted Steel Plates Versus UHPFRC Overlay for Controlling Deflection in RC Shallow Beams with Planted Columns-Experimental Insights. [PDF]
Elsanadedy H +5 more
europepmc +1 more source
A Janus‐like bio‐inspired strategy is proposed for integrally 3D‐printed bimetallic metamaterials. Inspired by shell bilayers, a heat‐resistant AlSiFeMnNiMg alloy and a SiC‐reinforced AlSi10Mg with different SiC volume fractions are arranged as an architected pair.
Zhicheng Dong +5 more
wiley +1 more source
Deformable Eutectic Alloy With Near-Theoretical Yield Strength via Hierarchical Nanoscale Multiphases and Sessile Defects. [PDF]
Luo Y +10 more
europepmc +1 more source
This study investigates acoustic phonon‑carrier coupling in FAxMA1−xPbBr3 single crystals using time‑domain Brillouin scattering. The results show that increasing the FA content in FAxMA1−xPbBr3 single crystal reduces both the elastic constant and the intrinsic carrier mobility governed by the acoustic phonon‑carrier coupling.
Wei Zhang +7 more
wiley +1 more source
Numerical investigation on the torsional improvement of reinforced concrete beams strengthened with various techniques. [PDF]
Yusuf MA, Zahran MS, Osman A, Nagy NM.
europepmc +1 more source
In this work, a bioinspired all‐in‐one underwater quality evaluation metamaterial, combining sound attenuation, diffuse reflection, and mechanical robustness, is proposed based on jumping spider locomotion and human skeletal biomechanics. Meanwhile, a CNN‑driven quality evaluation framework is established for theoretically dimension‐reduced ...
Hongze Li +8 more
wiley +1 more source
Atomistic investigation of grain boundary strengthening and composition-dependent mechanical properties in CuNi binary alloys. [PDF]
Mim SN, Hossain Z, Ali ML.
europepmc +1 more source
Annealing‐Induced Plasticity and Strengthening in Metallic Glasses
This work challenges the dogma that annealing inevitably embrittles metallic glasses. We demonstrate that sub‐Tg annealing, guided by positive mixing enthalpy and constrained kinetics, can drive a self‐organized compositional fluctuation that creates an interface‐free heterogeneous structure.
Yingjie Zhang +17 more
wiley +1 more source
Performance of HSC Continuous Deep Beams with Asymmetric Circular Openings: Hybrid FRP Versus Steel Plate Strengthening. [PDF]
Al-Mahbashi M +5 more
europepmc +1 more source

