Results 181 to 190 of about 1,358 (245)

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

BMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen, Tao Li, Zhongyou Li, Jingyuan Zhou, Zhuo Zhang, Yan Xiong, Rifang Luo, Yu Chen, Yunbing Wang, Ping Fu   +9 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Circular Innovations in Complex Systems: A Blueprint of Four Design Archetypes

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular innovations (CI), defined as the redesign of products, services or practices to minimise waste, reduce resource use and regenerate natural systems, are essential for advancing the circular economy. Despite growing recognition, their deployment in systems of linked parts with unpredictable interactions (complex systems) remains limited
Sophie Führer, Lucas Miehé, Catharina Bening   +2 more
wiley   +1 more source

Ensemble‐based soil liquefaction assessment: Leveraging CPT data for enhanced predictions

Civil Engineering Design, Volume 7, Issue 1, Page 23-35, March 2025.
Abstract This study focuses on predicting soil liquefaction, a critical phenomenon that can significantly impact the stability and safety of structures during seismic events. Accurate liquefaction assessment is vital for geotechnical engineering, as it informs the design and mitigation strategies needed to safeguard infrastructure and reduce the risk ...
Arsham Moayedi Far, Masoud Zare
wiley   +1 more source

Multifunctional Design of Solid Polymer Electrolytes: Paving the Way for High‐Performance All‐Solid‐State Batteries

Carbon Energy, EarlyView.
This review provides a comprehensive and systematic overview of the multifunctional design strategies for solid polymer electrolytes (SPEs), a pivotal component for enabling high‐performance all‐solid‐state batteries (ASSBs). It begins with a detailed classification of SPE systems and elaborates on their respective molecular design principles. The work
Bin Man, Yuzhen Zhao, Bo Fu, Yulong Zeng, Yinwen Chen, Qingrui Liu, Wenjing Luo, Xin Li, Xuewei Li, Zikang Zhang, Yun Zheng, Sijie Liu   +11 more
wiley   +1 more source

The Filament Extension Atomization Process for Powder Production of Elastic Fluids

Chemie Ingenieur Technik, EarlyView.
Filament extension atomization is a promising technique for spraying a wide range of materials, enabling narrow droplet size distributions. This study examines the behavior of various fluids and suspensions to define application limits and identify optimal operating conditions.
Moritz Neukötter, Nick Aulbur, Julian Neudorf, Steffen Jesinghausen, Hans‐Joachim Schmid   +4 more
wiley   +1 more source

Comparative assessment of volume‐of‐fluid (VOF) multiphase solvers for viscoplastic flow over grooved patterned surfaces

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Accurately simulating multiphase flows at low capillary numbers remains challenging due to spurious currents and interface discretization errors. We present a systematic comparison of four volume‐of‐fluid (VOF) solvers within the OpenFOAM framework for pressure‐driven Poiseuille–Bingham flow over grooved surfaces: interFoam with classical ...
Amir Joulaei, Alice Villette, Seyed Mohammad Taghavi   +2 more
wiley   +1 more source

Directional and gradient patterning from sub‐microliter colloidal droplet evaporation on inclined and stretched soft substrates

Droplet, EarlyView.
Instead of suppressing the ubiquitous “coffee‐ring” effect, we harness it by integrating stretching, inclination, and rotation of soft substrates. This sequential control allows manipulation of global pattern symmetry and local morphology. By incorporating substrate inclination and rotation of stretched soft substrates, we create diverse patterns that ...
Wandong Bai, Yujun Lin, Yixuan Du, Yufei Fang, Feiyang Zhang, Elmar Bonaccurso, Wei Xiao, Yue Shen, Günter K. Auernhammer, Xuehua Zhang, Binyu Zhao   +10 more
wiley   +1 more source