Results 141 to 150 of about 2,827,082 (381)

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim   +9 more
wiley   +1 more source

The performance analysis of shear walls with opening based on quantitative identification method of vibration modes

open access: yesAlexandria Engineering Journal
Shear walls are the main lateral force resistant components of building structures. The position and shape of openings seriously affect the performance of shear walls.
Panxu Sun   +3 more
doaj  

Experimental Study on the Effects of Water-in-oil Emulsions to Wall Shear Stress in the Pipeline Flow

open access: yesJournal of Applied Fluid Mechanics, 2018
Study on the emulsion formation mechanically and relate the effect of emulsions to the friction or wall shear stress ( ) in the pipeline flow has not yet been explored.
S. S. Dol   +3 more
doaj  

The simulation of coherent structures in a laminar boundary layer [PDF]

open access: yes
Coherent structures in turbulent shear flows were studied extensively by several techniques, including the VITA technique which selects rapidly accelerating or decelerating regions in the flow.
Breuer, Kenny   +2 more
core   +1 more source

Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui   +19 more
wiley   +1 more source

Seismic Performance Evaluation of Reinforced Concrete Frame–Shear Wall Structural Systems in Thermal Power Plants

open access: yesBuildings
The seismic performance of an electric power system is crucial for maintaining the functionality of urban communities following an earthquake. In thermal power plants, the RC frame–shear wall structure plays a key role in providing seismic resistance to ...
Zhongming Xiong, Jiawei Liang, Xuan Chen
doaj   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman   +6 more
wiley   +1 more source

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

The Role of Sex Hormones in Inducing Maternal Uterine Remodeling and Vasodilation During Pregnancy [PDF]

open access: yes, 2018
Uterine vascular adaptations such as vessel growth and vasodilation are needed to facilitate the more than 10-fold increase of uteroplacental blood flow (UPBF) during pregnancy.
Glessner-Fischer, Annie D.
core   +1 more source

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