Results 111 to 120 of about 1,131,795 (383)

NKG2D and MICA/B shedding: a ‘tag game’ between NK cells and malignant cells

open access: yesClinical & Translational Immunology, 2020
Natural killer (NK) cells are innate lymphocytes with cytotoxic functions and recognise target cells with the NK group 2D (NKG2D) receptor. Tumor cells are marked for NK‐cell‐mediated destruction upon expression of MICA and MICB (MICA/B), which are NKG2D
Samantha Xing, Lucas Ferrari de Andrade
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Shedding of porcine circovirus type 1 DNA and rotavirus RNA by infants vaccinated with Rotarix®

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Thirty-three infants aged ∼2 months had serial stool samples collected after receipt of Rotarix® vaccine dose 1, and were assessed for shedding of porcine circovirus type 1 DNA and Rotavirus group A RNA by molecular methods.
Slavica Mijatovic-Rustempasic   +8 more
doaj   +1 more source

Experimental Inoculation of Egyptian Fruit Bats (Rousettus aegyptiacus) with Ebola Virus

open access: yesViruses, 2016
Colonized Egyptian fruit bats (Rousettus aegyptiacus), originating in South Africa, were inoculated subcutaneously with Ebola virus (EBOV). No overt signs of morbidity, mortality, or gross lesions were noted.
Janusz T. Paweska   +5 more
doaj   +1 more source

Investigation of a drag reduction on a circular cylinder in rotary oscillation [PDF]

open access: yes, 2001
Drag reduction in two-dimensional flow over a circular cylinder, achieved using rotary oscillation, was investigated with computational simulations. In the experiments of Tokumaru & Dimotakis (1991), this mechanism was observed to yield up to 80% drag ...
Leonard, A., Shiels, D.
core   +1 more source

Alternative ORFs and small ORFs: shedding light on the dark proteome.

open access: yesNucleic Acids Research, 2019
Traditional annotation of protein-encoding genes relied on assumptions, such as one open reading frame (ORF) encodes one protein and minimal lengths for translated proteins.
M. Orr   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

EVALUATION OF RECOMBINANT AVIAN INFLUENZA COMPARED TO INACTIVATED VACCINES TO INDUCE IMMUNE RESPONSE IN CHICKEN [PDF]

open access: yesArab Universities Journal of Agricultural Sciences, 2018
The present Avian Influenza epidemic in Egypt is consider one of the major problems facing the poultry field and caused by circulation of genetically and antigenetically diverse influenza H5N1 viruses.
Dalia Omar, K. El-Dougdoug, B. Othman
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Shedding and extensive and prolonged environmental contamination of goat farms of Q fever patients by Coxiella burnetii

open access: yesVeterinary Medicine and Science, 2022
Background A majority (>70%) of Q fever patients in South Korea do not have a history of animal contact. Therefore, unconscious environmental exposure is suspected.
Hyeon Seop Byeon   +9 more
doaj   +1 more source

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