Results 191 to 200 of about 2,529,828 (312)

Sprayable MXene Hydrogels With Composition‐Driven Interfacial Stabilization and on‐Skin Gelation for Conformal Postsurgical Photothermal Therapy

open access: yesSmall, EarlyView.
A sprayable MXene‐loaded thermosensitive hydrogel was developed for postoperative melanoma treatment. Molecular simulations combined with experimental analyses demonstrated that polymer composition regulates MXene oxidation. The optimized hydrogel effectively preserved photothermal performance under physiological conditions, enabling efficient near ...
Taek Hwang   +15 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Modification and expansion of existing body condition scoring scales for rabbits (Oryctolagus cuniculus) improves inter‐rater reliability when used by experienced raters

open access: yesVeterinary Record, EarlyView.
Abstract Background Reliable body condition scoring in rabbits is essential in managing healthy bodyweight. The commonly used Rabbit size‐o‐meter (RSOM) has shown poor inter‐rater reliability, particularly among inexperienced raters. This study aimed to develop a reliable, reproducible body condition scoring scale for companion rabbits across breeds ...
Mette L. Halck   +6 more
wiley   +1 more source

Abattoir antemortem inspection protocol: Observation of unloading improves detection of transport welfare compromises in livestock

open access: yesVeterinary Record, EarlyView.
Abstract Background Ensuring livestock welfare throughout the production chain, including transport, is an ethical and regulatory imperative. However, protocols to assess transport‐related welfare during routine abattoir inspections are not standardised, including antemortem (AM) inspection by an official veterinarian at UK abattoirs.
Sayaka Mochizuki   +2 more
wiley   +1 more source

Assessing veterinary students’ attitudes towards pain in cattle before and after final‐year clinical training

open access: yesVeterinary Record, EarlyView.
Abstract Background Cattle only show subtle signs of pain, making pain assessment difficult. The approach to pain and the use of analgesics depend on the treating person's experience and opinions. Methods Bavarian veterinary students were asked to answer two identical questionnaires before and after 12 weeks of clinical training in a ruminant clinic. A
Theresa Tschoner   +3 more
wiley   +1 more source

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