Results 41 to 50 of about 30,106 (301)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Misturas físicas de polipropileno com aditivos condutores: obtenção, caracterização e aplicação para blindagem eletromagnética [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência e Engenharia de MateriaisMisturas poliméricas condutoras de eletricidade, à base de polipropileno (PP) aditivado com negro de ...
Martins, Nilda
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Measurement of the transient shielding effectiveness of enclosures using UWB pulses inside an open TEM waveguide [PDF]

Advances in Radio Science, 2007
Recently, new definitions of shielding effectiveness (SE) for high-frequency and transient electromagnetic fields were introduced by Klinkenbusch (2005). Numerical results were shown for closed as well as for non closed cylindrical shields.
H. Herlemann, M. Koch
doaj  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

PANI-wrapped BaFe12O19 and SrFe12O19 with rGO composite materials for electromagnetic interference shielding applications

Heliyon, 2023
We report electromagnetic interference (EMI) shielding efficiency in the PANI-wrapped BaFe12O19 and SrFe12O19 with rGO composites. Barium and strontium hexaferrites were synthesized using the nitrate citrate gel combustion method. These hexaferrites were
G.P. Abhilash, Devansh Sharma, Suryasarathi Bose, C. Shivakumara   +3 more
doaj   +1 more source

Shielding effectiveness of carbon-filled polypropylene composites

, 2016
© SAGE Publications. Adding conductive carbon fillers to insulating thermoplastic resins increases composite shielding effectiveness. In this study, varying amounts of three different carbons (carbon black, synthetic graphite particles, and carbon ...
King, Julia A., Pisani, William A., Turpeinen, Dylan G., Odegard, Gregory M., Perger, Warren F., Klimek-Mcdonald, Danielle R.   +5 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effect of fiber hybridization on the electromagnetic shielding of UHPFRCC panel

Journal of Materials Research and Technology
Interest in electromagnetic shielding of cement-based materials is increasing to protect human health and electronic equipment from electromagnetic interference (EMI).
Ho-Jin Lee, Jin-Seok Choi, Doo-Yeol Yoo, Young-Soo Yoon   +3 more
doaj   +1 more source