Results 51 to 60 of about 106,477 (297)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
An Experimental Investigation of the use of Q-Factor to Determine the Shielding Effectiveness of Electrically Large Equipment Enclosures with Apertures [PDF]
, 2011 The current method of obtaining a Shielding Effectiveness (SE) measurement involves field measurements both inside and outside the enclosure to be tested. In this paper, a relationship between the Shielding Effectiveness and the Q-factor of the enclosure
Armstrong, Robert +2 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Estimation of the EMR shielding effectiveness of knit structures [PDF]
, 2012 This paper describes the creation of and tests petformed on knit structures of three types (left-right stitch (I), double-layer (II), and double-layer with additional fillings (III)), which contain ferromagnetic materials and electroconductive materials ...
Ciesielska-Wrobel, Izabela +1 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Electromagnetic losses in magnetic shields for buried high voltage cables [PDF]
, 2011 The electromagnetic losses and shielding efficiency of shields for a buried three phase high voltage cable are studied for several shielding configurations.
Koroglu, Selim, Sergeant, Peter
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Heliyon, 2023 We report electromagnetic interference (EMI) shielding efficiency in the PANI-wrapped BaFe12O19 and SrFe12O19 with rGO composites. Barium and strontium hexaferrites were synthesized using the nitrate citrate gel combustion method. These hexaferrites were
G.P. Abhilash +3 more
doaj +1 more source
Atom Interferometry in Space: Thermal Management and Magnetic Shielding
, 2014 Atom interferometry is an exciting tool to probe fundamental physics. It is considered especially apt to test the universality of free fall by using two different sorts of atoms. The increasing sensitivity required for this kind of experiment sets severe
Braxmaier, Claus +6 more
core +1 more source