Results 31 to 40 of about 56,619 (260)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Blind Estimation of Self-Synchronous Scrambler in DSSS Systems
IEEE Access, 2021 Self-synchronous scramblers are more difficult to blindly estimate than synchronous scramblers because their input sequence affects the state of the scrambler’s linear feedback shift register.
Dongyeong Kim, Dongweon Yoon
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
On the Estimation of Synchronous Scramblers in Direct Sequence Spread Spectrum Systems
IEEE Access, 2020 In a non-cooperative context, the receiver has no information about communication parameters; therefore, it must perform communication forensics, which is the process of identifying what information it can from the collected data.
Dongyeong Kim +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Novel level and edge-triggered universal shift registers with low latency in QCA technology
HeliyonShift registers are one of the main blocks in processors. In this paper, two new universal shift registers are designed based on Quantum-Dot Cellular Automata (QCA) nanotechnology.
Mojtaba Gholamnia Roshan +1 more
doaj +1 more source
Mode in Arabic-English Translation: with Reference to the Quran
Russian journal of linguistics: Vestnik RUDN, 2019 A rhetorical question has the form of a question but does not perform its function, i.e. does not seek any information but rather, is used to give a specific or rhetoric function such as denial, assertion, testing, equalization and negation.
Ibrahim II Najjar +2 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
5‐T and 6‐T thermometer‐code latches for thermometer‐code shift‐register
ETRI Journal, 2021 This paper proposes thermometer‐code latches having five and six transistors for unidirectional and bidirectional thermometer‐code shift‐registers, respectively.
Ki‐Chan Woo, Byung‐Do Yang
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source