Results 51 to 60 of about 193,280 (290)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Digital data reformatter/deserializer [PDF]
, 1979 A method and apparatus is presented for reformatting and de-serializing a serially-received sequence of data words, each consisting of a fixed number of binary data bits.
Engel, A., Springer, L. R.
core +1 more source
Duality of Channel Encoding and Decoding - Part I: Rate-1 Binary Convolutional Codes
, 2016 In this paper, we revisit the forward, backward and bidirectional Bahl-Cocke-Jelinek-Raviv (BCJR) soft-input soft-output (SISO) maximum a posteriori probability (MAP) decoding process of rate-1 binary convolutional codes.
Bahl +7 more
core +1 more source
Branch prediction apparatus, systems, and methods [PDF]
, 2011 An apparatus and a system, as well as a method and article, may operate to predict a branch within a first operating context, such as a user context, using a first strategy; and to predict a branch within a second operating context, such as an operating ...
John, Lizy K., Li, Tao
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Theory and application of feedback shift registers [PDF]
, 1971 Document summarizes state-of-the-art in data processing techniques on-board spacecraft, and serves as an aid for personnel requiring tutorial knowledge of ultrareliable data processing ...
Perlman, M.
core +1 more source
Field-free deterministic ultra fast creation of skyrmions by spin orbit torques
, 2017 Magnetic skyrmions are currently the most promising option to realize current-driven magnetic shift registers. A variety of concepts to create skyrmions were proposed and demonstrated. However, none of the reported experiments show controlled creation of
A Brataas +41 more
core +2 more sources
Realizing arbitrary-precision modular multiplication with a fixed-precision multiplier datapath [PDF]
, 2009 Within the context of cryptographic hardware, the term scalability refers to the ability to process operands of any size, regardless of the precision of the underlying data path or registers.
Grossschaedl, Johann +4 more
core +2 more sources