Results 81 to 90 of about 193,280 (290)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

REGISTERS OF CHEFS‟ SPOKEN LANGUAGE IN TELEVISION COOKING SHOWS: A PHENOMENON OF LANGUAGE SHIFTING [PDF]

open access: yes, 2011
Register bahasa lisan yang biasa digunakan oleh para koki dalam acara-acara memasak di televisi sangat menarik untuk dikaji. Istilah-istilah kuliner sepertinya mengalami perkembangan secara drastis dari waktu ke waktu.
Yulianti, Andi Indah
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Opposite direction multiple-phase clocking in adjacent CCD shift registers [PDF]

open access: yes, 1987
Parallelled charge transfer channels have multiple-phase-clocked gate electrodes overspanning them in one of a number of arrangements conditioning the transfer of charge packets in opposing directions in adjacent charge transfer channels.
Elabd, Hammam
core   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

On the Equivalence Between Canonical Forms of Recursive Systematic Convolutional Transducers Based on Single Shift Registers

open access: yesIEEE Access, 2014
Standardized turbo codes (TCs) use recursive systematic convolutional transducers of rate b/(b + d), having a single feedback polynomial (b+dRSCT). In this paper, we investigate the realizability of the b+dRSCT set through two single shift register ...
Horia Balta   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

« Alzarse » : les formes d’une pratique, depuis l’époque des palenques jusqu’à l’extinction des derniers groupes de guérilleros anticastristes

open access: yesNuevo mundo - Mundos Nuevos, 2008
This article hinges upon historical analysis to describe the complexity of the alzamientos ("uprisings") that took place in Cuba between 1959 and 1965 by reflecting on the way in which they intermingled practices anchored in long-term local history ...
Vincent Bloch
doaj   +1 more source

Adaptive voting computer system [PDF]

open access: yes, 1974
A computer system is reported that uses adaptive voting to tolerate failures and operates in a fail-operational, fail-safe manner. Each of four computers is individually connected to one of four external input/output (I/O) busses which interface with ...
Koczela, L. J., Wilgus, D. S.
core   +1 more source

Home - About - Disclaimer - Privacy