Results 81 to 90 of about 193,280 (290)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
REGISTERS OF CHEFS‟ SPOKEN LANGUAGE IN TELEVISION COOKING SHOWS: A PHENOMENON OF LANGUAGE SHIFTING [PDF]
Register bahasa lisan yang biasa digunakan oleh para koki dalam acara-acara memasak di televisi sangat menarik untuk dikaji. Istilah-istilah kuliner sepertinya mengalami perkembangan secara drastis dari waktu ke waktu.
Yulianti, Andi Indah
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Fabrication of an eight-pole commutator, associated shift register, control logic subsystem Quarterly technical report, 28 Sep. - 31 Oct. 1966 [PDF]
Preliminary study of alternate shift registers for eight-pole ...
Aronson, B.
core +1 more source
Opposite direction multiple-phase clocking in adjacent CCD shift registers [PDF]
Parallelled charge transfer channels have multiple-phase-clocked gate electrodes overspanning them in one of a number of arrangements conditioning the transfer of charge packets in opposing directions in adjacent charge transfer channels.
Elabd, Hammam
core +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Standardized turbo codes (TCs) use recursive systematic convolutional transducers of rate b/(b + d), having a single feedback polynomial (b+dRSCT). In this paper, we investigate the realizability of the b+dRSCT set through two single shift register ...
Horia Balta +2 more
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
This article hinges upon historical analysis to describe the complexity of the alzamientos ("uprisings") that took place in Cuba between 1959 and 1965 by reflecting on the way in which they intermingled practices anchored in long-term local history ...
Vincent Bloch
doaj +1 more source
Adaptive voting computer system [PDF]
A computer system is reported that uses adaptive voting to tolerate failures and operates in a fail-operational, fail-safe manner. Each of four computers is individually connected to one of four external input/output (I/O) busses which interface with ...
Koczela, L. J., Wilgus, D. S.
core +1 more source

