Results 211 to 220 of about 1,577,013 (279)

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

A Mixed Integer Programming Approach for Shift Scheduling in the Food Manufacturing Industry: A Real Case Study from Adana, Türkiye

HEDİYE KIRLI AKIN, Başak Polat Sevgi
  +4 more sources

Simulated shift work schedules disrupts circadian rhythms and behavior in mice

Jun-Yi Duan, Xiao-Tong Huang, Ai-Yu Duan, Ma Li, Wei Chen, Qun Luo   +5 more
openalex   +1 more source

Shift Work and Psychological Distress Among Healthcare Workers: The Mediating Role of Sleep Quality and the Association with Job Dissatisfaction. [PDF]

Healthcare (Basel)
Bakırhan F, Küçükkelepçe O.
europepmc   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Association Between Night-Shift Schedules, Nurse WellBeing, and Perceived Patient Care Quality Among ICU Nurses: A Cross-Sectional Study

Yasser Adnan Abu Jaish, Hasnaa Saleh Ahmed   +1 more
openalex   +1 more source

Shift Work, Circadian Disruption, and Immune Dysregulation: Molecular Links to Gastrointestinal Diseases and Occupational Health Implications. [PDF]

Diagnostics (Basel)
Boicea Camen AR, Caragea DC, Boldeanu MV, Florescu DN, Assani MZ, Siloși I, Boldeanu L.   +6 more
europepmc   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Global Shift Scheduling & Labor Law Compliance Dataset

Daywatch Research Team
openalex   +2 more sources

Fairness Decisions in Shift Scheduling: Comparing Equality, Equity, and different Needs

Anna Milena Rothermel, Astrid Marieke Rosenthal-Von Der Pütten, Christoph Naefgen   +2 more
openalex   +1 more source