Results 51 to 60 of about 293,216 (302)
Differences in the land rent among EU countries
The aim of the paper is to assess the differences in the influence of land rent on farm production efficiencies by region, farming type and LFA. In terms of the cost of rents there are significant differences among countries within the European Union ...
Jana Lososová +2 more
doaj +1 more source
Determining Leading Economic Sectors, by Large Distribution or Extreme Growth?
Leading economic sector on Tulungagung Regency determined by sector contribution on GRDP. These sectors expected can be a booster to economic growth. But Economic Growth in Tulungagung Regency was still slower than East Java Province.
Alfian Rosadi
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Shift-Share Analysis: Review of Spatial Versions
The article presents the genesis of spatial shift-share analysis. The author focuses on the links of spatial versions of shift-share analysis with the classical one, which is not just a starting point for them from a historical point of view, but retains the status of their constituent element.
openaire +1 more source
The spatial shift-share analysis - new developments and some findings for the Spanish case [PDF]
The main feature of shift-share analysis is, according to Dunn (1960), the computation of geographical shifts in economic activity. Nevertheless, the traditional shift-share approach does not include explicitly the interaction between the considered ...
Ana Jesús López Menéndez +1 more
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Europäische Metropolregionen in Deutschland – eine regionalökonomische Evaluation
For more than ten years the concept of European Metropolitan Regions is fixed in the German regional planning system. This article uses the shift-share-technique to assess the economic performance of the eleven German metropolitan areas based on a ...
Karsten M. Rusche, Christian A. Oberst
doaj +1 more source
Defining Scenarios through shift - share models. An Application to the regional employment [PDF]
The analysis of different economic situations and risk factors is necessary in order to properly define forecasting scenarios. In this paper we focus on the shift-share model as a useful tool in the definition of economic scenarios, based on the ...
Rigoberto Pérez Suárez +2 more
core

