Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Dynamic externalities and regional manufacturing development: An exploration of the Polish experience before and after 1989 [PDF]
The impact of localization and urbanization economies on regional manufacturing development in Poland 1976-96 is assessed in terms of employment and the regional convergence or divergence of the economy. We examine current research on the role of dynamic
Jon M. Steineke, Roger Bivand
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Changes in Communication after Transition from Paging to Collaborative Text Messaging. [PDF]
Sarma D +4 more
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Ethical Reflections on Co‑Authoring With People With Lived Experience Across Health, Education and Community Settings. [PDF]
Moss H +4 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
A Japanese-Dietitian Prompt Systematically Shifts Portion Estimates in LLM-Based Nutrient Estimation from Food Images: A Multi-Dataset, Multi-Model Study. [PDF]
Nakagawa S, Yamamoto A.
europepmc +1 more source
The high-quality development of marine fisheries is an important embodiment of building a maritime power. Using dynamic shift-share analysis method, this paper analyzes the overall performance of the growth rate, structure and competitiveness of seven ...
HAO Yuwan, SHEN Na, WANG Haizhuang
doaj

